Monica Fung, MD
Associate Professor
Monica Fung specializes in infectious diseases with a focus on patients with compromised immune systems, including those with solid organ or stem cell transplants. She attends on the Immunocompromised and General Infectious Diseases Consult Services, and has clinics in the 360 Wellness Center and Infectious Diseases Faculty Practice at UCSF-Parnassus.
RESEARCH AND EDUCATIONAL PURSUITS
Monica serves as Co-Director of the Transplant/Immunocompromised Host Infectious Diseases Program. Her research focuses the application of novel diagnostics to improve diagnosis of infections among transplant recipients. She directs the Transplant/Immunocompromised Host track within the UCSF Infectious Diseases Fellowship Program, and serves as a small group leader for the Pathogen Host Defense course in the School of Medicine.
Education
Publications
Pickering H, Schaenman J, Phan HV, Maguire C, Tsitsiklis A, Rouphael N, Higuita NIA, Atkinson MA, Brakenridge S, Fung M, Messer W, IMPACC Network, Salehi-Rad R, Altman MC, Becker PM, Bosinger SE, Eckalbar W, Hoch A, Doni Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed EF, Langelier CR. Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients. 2025. PMID: 39794319
Kim RW, Gutierrez RA, Jacobson R, Babik JM, Fung M, Miller S, Haemel A. Optimizing Diagnostic Test Accuracy of Skin Tissue Assays in Cutaneous Invasive Fungal Disease. 2024. PMID: 39447754
Madut DB, Chemaly RF, Dadwal SS, Hill JA, Lee YJ, Haidar G, Luk A, Drelick A, Chin-Hong PV, Benamu E, Khawaja F, Nanayakkara D, Papanicolaou GA, Small CB, Fung M, Barron M, Davis T, McClain MT, Maziarz EK, Bedoya AD, Gilstrap DL, Todd JL, Barkauskas CE, Heldman MR, Bigelow R, Leimberger JD, Tsalik EL, Wolf O, Mughar M, Lau C, Noll N, Hollemon D, Duttagupta R, Lupu DS, Bercovici S, Perkins BA, Blauwkamp TA, Fowler VG, Holland TL, Bergin SP. Clinical Utility of Plasma Microbial Cell-Free DNA Sequencing Among Immunocompromised Patients With Pneumonia. 2024. PMID: 39091643
Fung M, Patel N, DeVoe C, Ryan CN, McAdams S, Pamula M, Dwivedi A, Teraoka J, Smollin M, Sam S, Perkins B, Chin-Hong P. Utility of Serial Microbial Cell-free DNA Sequencing for Inpatient and Outpatient Pathogen Surveillance Among Allogeneic Hematopoietic Stem Cell Transplant Recipients. 2024. PMID: 39086465
Fung M, La Hoz RM, Durand CM, Lee DH, Sears D, Hohe C, Chin-Hong P, Roberts JP. Successful Living Donor Liver Transplant from Donor with False-Positive HIV Test in Recipient without HIV. 2024. PMID: 38705516
Bergin SP, Chemaly RF, Dadwal SS, Hill JA, Lee YJ, Haidar G, Luk A, Drelick A, Chin-Hong PV, Benamu E, Khawaja F, Nanayakkara D, Papanicolaou GA, Small CB, Fung M, Barron MA, Davis T, McClain MT, Maziarz EK, Madut DB, Bedoya AD, Gilstrap DL, Todd JL, Barkauskas CE, Bigelow R, Leimberger JD, Tsalik EL, Wolf O, Mughar M, Hollemon D, Duttagupta R, Lupu DS, Bercovici S, Perkins BA, Blauwkamp TA, Fowler VG, Holland TL. Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients with Pneumonia: A Prospective Observational Study. 2023. PMID: 37815489
Lueking R, Fung M, Ramos-Salazar E, Katari S, Funk GA, Wolfe CR, La Hoz RM. Challenging Boundaries: Organ Transplants from Donors with Listeria Central Nervous System Infections. 2024. PMID: 38431076
Langelier C, Pickering H, Schaenman J, Phan H, Maguire C, Tsitsiklis A, Rouphael N, Higuita N, Atkinson M, Breckenridge S, Fung M, Messer W, Network I, Salehi-Rad R, Altman M, Becker P, Bosinger S, Eckalbar W, Hoch A, Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein S, Krammer F, Maecker H, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed E. Host-Microbe Multi-omic Profiling Identifies a Unique Program of COVID-19 Inflammatory Dysregulation in Solid Organ Transplant Recipients. 2023. PMID: 38196658
Mulliken JS, Hampshire KN, Rappold AG, Fung M, Babik JM, Doernberg SB. Risk of systemic fungal infections after exposure to wildfires: a population-based, retrospective study in California. 2023. PMID: 37164514
Sweeney DA, Tuyishimire B, Ahuja N, Beigel JH, Beresnev T, Cantos VD, Castro JG, Cohen SH, Cross K, Dodd LE, Erdmann N, Fung M, Ghazaryan V, George SL, Grimes KA, Hynes NA, Julian KG, Kandiah S, Kim HJ, Levine CB, Lindholm DA, Lye DC, Maves RC, Oh MD, Paules C, Rapaka RR, Short WR, Tomashek KM, Wolfe CR, Kalil AC. Baricitinib Treatment of Coronavirus Disease 2019 Is Associated With a Reduction in Secondary Infections. 2023. PMID: 37206623
Roland LT, Humphreys IM, Le CH, Babik JM, Bailey CE, Ediriwickrema LS, Fung M, Lieberman JA, Magliocca KR, Nam HH, Teo NW, Thomas PC, Winegar BA, Birkenbeuel JL, David AP, Goshtasbi K, Johnson PG, Martin EC, Nguyen TV, Patel NN, Qureshi HA, Tay K, Vasudev M, Abuzeid WM, Hwang PH, Jafari A, Russell MS, Turner JH, Wise SK, Kuan EC. Diagnosis, prognosticators, and management of acute invasive fungal rhinosinusitis: multidisciplinary consensus statement and Evidence-Based review with recommendations. 2023. PMID: 36680469
Katrak S, Han E, Readhead A, Fung M, Keh C, Flood J, Barry P. Solid organ transplant recipients with tuberculosis disease in California, 2010 to 2020. 2022. PMID: 36695700
Fung M, DeVoe C, Spottiswoode N, Doernberg SB. Maribavir for Cytomegalovirus Treatment in the Real World-Not a Silver Bullet. 2022. PMID: 36632422
DeVoe C, Pandey S, Shariff D, Arora S, Henrich TJ, Yokoe DS, Langelier CR, Servellita V, Chiu C, Miller S, Babik JM, Chin-Hong P, Fung M. COVID-19 in Vaccinated Versus Unvaccinated Hematologic Malignancy Patients. 2022. PMID: 35426225
Serpa PH, Deng X, Abdelghany M, Crawford E, Malcolm K, Caldera S, Fung M, McGeever A, Kalantar KL, Lyden A, Ghale R, Deiss T, Neff N, Miller SA, Doernberg SB, Chiu CY, DeRisi JL, Calfee CS, Langelier CR. Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections. 2022. PMID: 35818068
Chan JL, Nazarian E, Musser KA, Snavely EA, Fung M, Doernberg SB, Pouch SM, Leekha S, Anesi JA, Kodiyanplakkal RP, Turbett SE, Walters MS, Epstein L. Prevalence of carbapenemase-producing organisms among hospitalized solid organ transplant recipients, five U.S. hospitals, 2019-2020. 2022. PMID: 34989092
Crossman H, Guterman E, Fung M. Delayed diagnosis and treatment of secondary syphilis in pancreas-kidney transplant recipient: Need for increased awareness of sexually transmitted infections in solid organ transplantation. 2021. PMID: 34797024
Mehta N, Gerdts J, Fung M, Guterman EL. Brain Abscess Caused by Bordetella hinzii. 2021. PMID: 34840911
Bainbridge ED, Hsue PY, Esensten JH, Lynch KL, Hendrickson CM, Doernberg SB, Fung M, Chin-Hong P, Di Germanio C, Norris PJ, Simmons G, Glidden DV, Luetkemeyer AF. Characteristics of High-Titer Convalescent Plasma and Antibody Dynamics After Administration in Patients With Severe Coronavirus Disease 2019. 2021. PMID: 34405093
Plonowska-Hirschfeld KA, Fung M, Glastonbury C, Ha PK. Parapharyngeal tuberculoid mass: A rare complication of Bacillus Calmette-Guérin therapy for urothelial carcinoma in situ. 2021. PMID: 34194767
Bond AR, Bainbridge E, Doernberg SB, Babik JM, Miller S, Khanafshar E, Henry T, David A, Russell M, Brandman D, Sherman CB, Yao F, Fung M. Disseminated Legionella micdadei Infection in a Liver Transplant Patient Presenting as Pulmonary Nodules and a Laryngeal Lesion. 2021. PMID: 33434394
Fung M, Babik JM. COVID-19 in Immunocompromised Hosts: What We Know So Far. 2021. PMID: 33501974
June L Chan, Elizabeth Nazarian, Kimberlee A Musser, Monica Fung, Sarah B Doernberg, Stephanie M Pouch, Stephanie M Pouch, Surbhi Leekha, Judith A Anesi, Rosy Priya Kodiyanplakkal, Sarah Turbett, Maroya Spalding Walters, Lauren Epstein, Lauren Epstein. 918. Pilot Surveillance for Carbapenemase Gene-positive Organisms Among Hospitalized Solid Organ Transplant Recipients. 2020. PMID:
Fung M, Otani I, Pham M, Babik J. Zoonotic coronavirus epidemics: SARS, MERS, and COVID-19. 2020. PMID: 33310180
Fung M, Nambiar A, Pandey S, Aldrich JM, Teraoka J, Freise C, Roberts J, Chandran S, Hays SR, Bainbridge E, DeVoe C, Gardner AR, Yokoe D, Henrich TJ, Babik JM, Chin-Hong P. Treatment of Immunocompromised COVID-19 patients with Convalescent Plasma. 2020. PMID: 32989856
Iasella CJ, Hoji A, Popescu I, Wei J, Snyder M, Zhang Y, Xu W, Iouchmanov V, Koshy R, Brown M, Fung M, Langelier C, Lendermon EA, Dugger D, Shah R, Lee J, Johnson B, Golden J, Leard LE, Kleinhenz ME, Kilaru S, Hays SR, Singer JP, Sanchez PG, Morrell MR, Pilewski JM, Greenland JR, Chen K, McDyer JF. Type-1 Immunity and Endogenous Immune Regulators Predominate in the Airway Transcriptome during Chronic Lung Allograft Dysfunction. 2020. PMID: 33078555
Dugger DT, Fung M, Hays SR, Singer JP, Ellen Kleinhenz M, Leard LE, Golden JA, Shah RJ, Lee JS, Deiter F, Greenland NY, Jones KD, Langelier CR, Greenland JR. Chronic Lung Allograft Dysfunction Small Airways Reveal A Lymphocytic Inflammation Gene Signature. 2020. PMID: 32885581
Dugger DT, Fung M, Zlock L, Caldera S, Sharp L, Hays SR, Singer JP, Leard LE, Golden JA, Shah RJ, Kukreja J, Gordon E, Finkbeiner W, Kleinhenz ME, Langelier C, Greenland JR. Cystic Fibrosis Lung Transplant Recipients Have Suppressed Airway Interferon Responses during Pseudomonas Infection. 2020. PMID: 32754722
Fung M, Chiu CY, DeVoe C, Doernberg SB, Schwartz BS, Langelier C, Henrich TJ, Yokoe D, Davis J, Hays SR, Chandran S, Kukreja J, Ng D, Prostko J, Taylor R, Reyes K, Bainbridge E, Bond A, Chin-Hong P, Babik JM. Clinical Outcomes and Serologic Response in Solid Organ Transplant Recipients with COVID-19: A Case Series from the United States. 2020. PMID: 32476258
D.T. Dugger, M. Fung, L. Zlock, S. Caldera, S.R. Hays, J.P. Singer, L.E. Leard, J.A. Golden, R. Shah, J. Kukreja, W. Finkbeiner, M. Kleinhenz, C. Langelier, J.R. Greenland. Decreased Immune Activation in Cystic Fibrosis Airway Epithelium Following Lung Transplant. 2020. PMID:
Langelier C, Fung M, Caldera S, Deiss T, Lyden A, Prince BC, Hayakawa Serpa P, Moazed F, Chin-Hong P, DeRisi JL, Calfee CS. Detection of Pneumonia Pathogens from Plasma Cell-Free DNA. 2019. PMID: 31647702
Fung M, Babik J, Humphreys IM, Davis GE. Diagnosis and Treatment of Acute Invasive Fungal Sinusitis in Cancer and Transplant Patients. 2019. PMID: 31773398
Fung M, Jacobsen E, Freedman A, Prestes D, Farmakiotis D, Gu X, Nguyen PL, Koo S. Increased Risk of Infectious Complications in Older Patients With Indolent Non-Hodgkin Lymphoma Exposed to Bendamustine. Volume 68 of Issue 2. 2019. PMID: 29800121
Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL. Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults. 2018. PMID: 30482864
Fung M, Zompi S, Seng H, Hollemon D, Parham A, Hong DK, Bercovici S, Dolan E, Lien K, Teraoka J, Logan AC, Chin-Hong P. Plasma Cell-Free DNA Next-Generation Sequencing to Diagnose and Monitor Infections in Allogeneic Hematopoietic Stem Cell Transplant Patients. 2018. PMID: 30581881
Fung M, Schwartz BS, Doernberg SB, Langelier C, Lo M, Graff L, Tan M, Logan AC, Chin-Hong P, Babik JM. Breakthrough Invasive Fungal Infections on Isavuconazole Prophylaxis and Treatment: What Is Happening in the Real-World Setting? 2018. PMID: 29617983
Miller DC, Fung M, Carbo A. A Furry Friend's Dirty Mouth: Brain Abscess Due to Aggregatibacter (Haemophilus) aphrophilus. Volume 130 of Issue 10. 2017. PMID: 28528922
Monica Fung, Arnold Freedman, Daniel Prestes, Xiangmei Gu, Dimitrios Farmakiotis, Paul Nguyen, Sophia Koo. Infectious Complications Associated with Bendamustine Exposure in Patients with Indolent non-Hodgkin Lymphoma. 2016. PMID:
Sandora TJ, Fung M, Melvin P, Graham DA, Rangel SJ. National Variability and Appropriateness of Surgical Antibiotic Prophylaxis in US Children's Hospitals. Volume 170 of Issue 6. 2016. PMID: 27088649
Fung M, Kim J, Marty FM, Schwarzinger M, Koo S. Meta-Analysis and Cost Comparison of Empirical versus Pre-Emptive Antifungal Strategies in Hematologic Malignancy Patients with High-Risk Febrile Neutropenia. Volume 10 of Issue 11. 2015. PMID: 26554923
Sandora TJ, Fung M, Flaherty K, Helsing L, Scanlon P, Potter-Bynoe G, Gidengil CA, Lee GM. Epidemiology and risk factors for Clostridium difficile infection in children. Volume 30 of Issue 7. 2011. PMID: 21233782
Rangel SJ, Fung M, Graham DA, Ma L, Nelson CP, Sandora TJ. Recent trends in the use of antibiotic prophylaxis in pediatric surgery. Volume 46 of Issue 2. 2011. PMID: 21292089
Fung M, Scott KC, Kent CK, Klausner JD. Chlamydial and gonococcal reinfection among men: a systematic review of data to evaluate the need for retesting. Volume 83 of Issue 4. 2006. PMID: 17166889