Warner Greene, MD, PhD

Professor

Warner C. Greene, MD, PhD is Director of the Gladstone Center for HIV Cure Research, Senior Investigator, and Nick and Sue Hellmann Distinguished Professor of Translational Medicine at the Gladstone Institute of Virology and Immunology (GIVI). He is the Founding and Emeritus Director of GIVI. Dr. Greene is also Professor of Medicine, Microbiology and of Immunology at UCSF. Dr. Greene is a member of the Institute of Medicine of the National Academies and a fellow of the American Academy for the Advancement of Science. He also serves as Co-Director of the UCSF-Gladstone Center for AIDS Research, and has served as a Councilor and President of the Association of American Physicians. Dr. Greene earned a bachelor’s degree at Stanford University and an MD/PhD at Washington University School of Medicine. He took his internship and residency training in Medicine at the Massachusetts General Hospital at Harvard. After serving as a Senior Investigator at the National Cancer Institute and a Professor of Medicine and Howard Hughes Investigator at Duke University Medical Center, Dr. Greene accepted his current position as the Founding Director of the Gladstone Institute of Virology and Immunology in 1991. The ongoing research in Dr. Greene’s laboratory focuses on the molecular mechanisms underlying HIV pathogenesis, latency, and transmission. He is the author of more than 380 scientific papers and has been recognized as one of the 100 Most Cited Scientists in the world. In 2007, Dr. Greene expanded his work to include global health in sub-Saharan Africa in his service as president and executive chairman of the Accordia Global Health Foundation. Accordia established the Infectious Diseases Institute at Makerere University in Uganda, which has trained thousands of African health care workers, is caring for 30,000 HIV-infected patients, and has brought health care to nearly 500,000 people living in remote rural regions of Uganda. In 2016, Accordia merged with Africare.
Education
1979 - Internal Medicine Residency, Massachusetts General Hospital
1978 - Internal Medicine Internship, Massachusetts General Hospital
MD, PhD, 1977 - Medical Scientist Training Program, Washington University School of Medicine
BA, 1971 - , Stanford University
Honors and Awards
  • Lifetime Achievement Award for Scientific Contributions, Institute of Human Virology, 2019
  • • Honorary Doctoral Degree and Commencement Speaker, Drexel University, 2015
  • Elected as Member, American Academy of Arts & Sciences, 2014
  • Francis Gilman Blake Award, Association of American Physicians, 2013
  • President, Association of American Physicians, 2012-2013
  • Distinguished Research Career Award, Ohio State University Center for Retrovirus Research, 2012
  • Alumni Achievement Award, Washington University in St. Louis, 2012
  • Center Director, Global Virus Network, 2011-pres
  • President-Elect, Association of American Physicians, 2011-2012
  • Councilor, Association of American Physicians, 2005-2011
  • Elected as Member, National Academy of Medicine, 2005
  • Elected Fellow, American Association for the Advancement of Science, 2004
  • Honorary Co-Chair, AIDS Memorial Advisory Board, 2003-pres
  • Board of Directors, Academic Alliance Foundation, 2003-pres
  • Selected as Original Member, ISI Highly Cited Researchers, 2001
  • Executive Committee and Chair of Scientific Committee, Waterford Project, 2000
  • Institutional Representative, American Society for Clinical Investigation, 1998-2001
  • Member, Mayor's AIDS Scientific Advisory Council, 1997-1998
  • Co-Chair, Keystone AIDS Symposium, 1995
  • Co-Chair, Scientific Committee, 1st-3rd National Conferences on Human Retroviruses & Related Infections, 1994-1996
  • Vice President, American Society for Clinical Investigation, 1993-1994
  • Elected, California Academy of Medicine, 1993
  • Elected, Association of American Physicians, 1990
  • Recipient, Young Investigator Award, American Rheumatism Association, 1988
  • Recipient, Outstanding Investigator Award, American Federation for Clinical Research, 1987
  • Elected, American Society for Clinical Investigation, 1985
  • Recipient, Award in the Biological Sciences, Washington Academy of Sciences, 1984
  • 100 Most Cited Scientists, Institute for Scientific Information (Science Citation Index), 1981-1988
  • Elected Member, Alpha Omega Alpha, 1977
  • Prize in Medicine, St. Louis Internists, 1977
  • Research Honorary, Sigma Xi, 1976
  • Honors Program in Biology, Stanford University, 1970-1971
  • Recipient, Research Fellowship Award, California Heart Association, 1970
Websites
Publications

  1. Ryu JK, Yan Z, Montano M, Sozmen EG, Dixit K, Suryawanshi RK, Matsui Y, Helmy E, Kaushal P, Makanani SK, Deerinck TJ, Meyer-Franke A, Rios Coronado PE, Trevino TN, Shin MG, Tognatta R, Liu Y, Schuck R, Le L, Miyajima H, Mendiola AS, Arun N, Guo B, Taha TY, Agrawal A, MacDonald E, Aries O, Yan A, Weaver O, Petersen MA, Meza Acevedo R, Alzamora MDPS, Thomas R, Traglia M, Kouznetsova VL, Tsigelny IF, Pico AR, Red-Horse K, Ellisman MH, Krogan NJ, Bouhaddou M, Ott M, Greene WC, Akassoglou K. Fibrin drives thromboinflammation and neuropathology in COVID-19. 2024. PMID: 39198643


  2. Li L, Matsui Y, Prahl MK, Cassidy AG, Golan Y, Jigmeddagva U, Ozarslan N, Lin CY, Buarpung S, Gonzalez VJ, Chidboy MA, Basilio E, Lynch KL, Song D, Jegatheesan P, Rai DS, Govindaswami B, Needens J, Rincon M, Myatt L, Taha TY, Montano M, Ott M, Greene WC, Gaw SL. Neutralizing and binding antibody responses to SARS-CoV-2 with hybrid immunity in pregnancy. 2024. PMID: 39191763


  3. Kong W, Frouard J, Xie G, Corley MJ, Helmy E, Zhang G, Schwarzer R, Montano M, Sohn P, Roan NR, Ndhlovu LC, Gan L, Greene WC. Neuroinflammation generated by HIV-infected microglia promotes dysfunction and death of neurons in human brain organoids. 2024. PMID: 38737767


  5. Kong W, Montano M, Corley MJ, Helmy E, Kobayashi H, Kinisu M, Suryawanshi R, Luo X, Royer LA, Roan NR, Ott M, Ndhlovu LC, Greene WC. Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons. 2022. PMID: 36314791


  6. Montano M, Victor AR, Griffin DK, Duong T, Bolduc N, Farmer A, Garg V, Hadjantonakis AK, Coates A, Barnes FL, Zouves CG, Greene WC, Viotti M. SARS-CoV-2 can infect human embryos. 2022. PMID: 36104397


  7. Packard TA, Schwarzer R, Herzig E, Rao D, Luo X, Egedal JH, Hsiao F, Widera M, Hultquist JF, Grimmett ZW, Messer RJ, Krogan NJ, Deeks SG, Roan NR, Dittmer U, Hasenkrug KJ, Greene WC. CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir. 2022. PMID: 36073812


  8. George AF, McGregor M, Gingrich D, Neidleman J, Marquez RS, Young KC, Thanigaivelan KL, Greene WC, Tien PC, Deitchman AN, Spitzer TL, Roan NR. Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV. 2022. PMID: 36016345


  9. Nakanjako D, Castelnuovo B, Sewankambo N, Kakaire T, Brough RL, Katabira ET, Thomas DL, Quinn TC, Colebunders R, Greene WC, Ronald AR, Coutinho A, McAdam K, Serwadda D, Wabwire-Mangen F, Katongole-Mbidde E, Musoke P, Joloba M, McKinnell H, Kamya M, Mayanja-Kizza H, Manabe YC, Kambugu A. Infectious Diseases Institute at Makerere University College of Health Sciences: a case study of a sustainable capacity building model for health care, research and training. 2022. PMID: 36321127


  10. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and infancy. 2022. PMID: 35908075


  11. Matsui Y, Li L, Prahl M, Cassidy AG, Ozarslan N, Golan Y, Gonzalez VJ, Lin CY, Jigmeddagva U, Chidboy MA, Montano M, Taha TY, Khalid MM, Sreekumar B, Hayashi JM, Chen PY, Kumar GR, Warrier L, Wu AH, Song D, Jegatheesan P, Rai DS, Govindaswami B, Needens JM, Rincon M, Myatt L, Asiodu IV, Flaherman VJ, Afshar Y, Jacoby VL, Murtha AP, Robinson JF, Ott M, Greene WC, Gaw SL. Neutralizing antibody activity against SARS-CoV-2 variants in gestational age-matched mother-infant dyads after infection or vaccination. 2022. PMID: 35579965


  12. Luo X, Frouard J, Zhang G, Neidleman J, Xie G, Sheedy E, Roan NR, Greene WC. Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq. 2022. PMID: 35784348


  13. Suryawanshi RK, Chen IP, Ma T, Syed AM, Brazer N, Saldhi P, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, Kumar GR, Montano M, Gascon R, Tsou CL, Garcia-Knight MA, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, George AF, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna JA, Ott M. Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. 2022. PMID: 35584773


  14. Suryawanshi RK, Chen IP, Ma T, Syed AM, Simoneau CR, Ciling A, Khalid MM, Sreekumar B, Chen PY, George AF, Kumar GR, Montano M, Garcia-Knight MA, Brazer N, Saldhi P, Sotomayor-Gonzalez A, Servellita V, Gliwa A, Nguyen J, Silva I, Milbes B, Kojima N, Hess V, Shacreaw M, Lopez L, Brobeck M, Turner F, Soveg FW, Fang X, Maishan M, Matthay M, Morris MK, Wadford D, Hanson C, Greene WC, Andino R, Spraggon L, Roan NR, Chiu CY, Doudna J, Ott M. Limited cross-variant immunity after infection with the SARS-CoV-2 Omicron variant without vaccination. 2022. PMID: 35075459


  15. George AF, Luo X, Neidleman J, Hoh R, Vohra P, Thomas R, Shin MG, Lee MJ, Blish CA, Deeks SG, Greene WC, Lee SA, Roan NR. Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals. 2022. PMID: 35154118


  16. Prahl M, Golan Y, Cassidy A, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin C, Gonzalez V, Chidboy M, Warrier L, Buarpung S, Murtha A, Flaherman V, Greene W, Wu A, Lynch K, Rajan J, Gaw S. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. 2021. PMID: 34931183


  17. Prahl M, Golan Y, Cassidy AG, Matsui Y, Li L, Alvarenga B, Chen H, Jigmeddagva U, Lin CY, Gonzalez VJ, Chidboy MA, Warrier L, Buarpung S, Murtha AP, Flaherman VJ, Greene WC, Wu AHB, Lynch KL, Rajan J, Gaw SL. Evaluation of transplacental transfer of mRNA vaccine products and functional antibodies during pregnancy and early infancy. 2021. PMID: 34931197


  19. Ryu JK, Sozmen EG, Dixit K, Montano M, Matsui Y, Liu Y, Helmy E, Deerinck TJ, Yan Z, Schuck R, Acevedo RM, Spencer CM, Thomas R, Pico AR, Zamvil SS, Lynch KL, Ellisman MH, Greene WC, Akassoglou K. SARS-CoV-2 spike protein induces abnormal inflammatory blood clots neutralized by fibrin immunotherapy. 2021. PMID: 34671772


  23. Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee SA, Ghosn E, Lynch KL, Roan NR. Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. 2021. PMID: 34260965


  24. Egedal JH, Xie G, Packard TA, Laustsen A, Neidleman J, Georgiou K, Pillai SK, Greene WC, Jakobsen MR, Roan NR. Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection. 2021. PMID: 33976386


  25. Xie G, Luo X, Ma T, Frouard J, Neidleman J, Hoh R, Deeks SG, Greene WC, Roan NR. Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4+ T cell subsets in vivo. 2021. PMID: 33910003


  26. Neidleman J, Luo X, George AF, McGregor M, Yang J, Yun C, Murray V, Gill G, Greene WC, Vasquez J, Lee S, Ghosn E, Lynch K, Roan NR. Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19. 2021. PMID: 33532792


  27. Gramatica A, Schwarzer R, Brantley W, Varco-Merth B, Sperber HS, Hull PA, Montano M, Migueles SA, Rosenthal D, Hogan LE, Johnson JR, Packard TA, Grimmett ZW, Herzig E, Besnard E, Nekorchuk M, Hsiao F, Deeks SG, Snape M, Kiernan B, Roan NR, Lifson JD, Estes JD, Picker LJ, Verdin E, Krogan NJ, Henrich TJ, Connors M, Ott M, Pillai SK, Okoye AA, Greene WC. Evaluating a New Class of AKT/mTOR Activators for HIV Latency Reversing Activity Ex Vivo and In Vivo. 2021. PMID: 33536176


  28. Li Z, Hajian C, Greene WC. Identification of unrecognized host factors promoting HIV-1 latency. 2020. PMID: 33270809


  29. Moron-Lopez S, Telwatte S, Sarabia I, Battivelli E, Montano M, Macedo AB, Aran D, Butte AJ, Jones RB, Bosque A, Verdin E, Greene WC, Wong JK, Yukl SA. Human splice factors contribute to latent HIV infection in primary cell models and blood CD4+ T cells from ART-treated individuals. 2020. PMID: 33253324


  30. Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, Milush J, James KS, Archin NM, Hunt PW, Deeks SG, Yukl SA, Palmer S, Greene WC, Roan NR. Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir. 2020. PMID: 32990219


  31. Neidleman J, Luo X, Frouard J, Xie G, Gill G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. SARS-CoV-2-specific T cells exhibit phenotypic features of robust helper function, lack of terminal differentiation, and high proliferative potential. 2020. PMID: 32839763


  32. Neidleman J, Luo X, Frouard J, Xie G, Gurjot G, Stein ES, McGregor M, Ma T, George AF, Kosters A, Greene WC, Vasquez J, Ghosn E, Lee S, Roan NR. SARS-CoV-2-specific T cells exhibit unique features characterized by robust helper function, lack of terminal differentiation, and high proliferative potential. 2020. PMID: 32577663


  33. Ma T, Luo X, George AF, Mukherjee G, Sen N, Spitzer TL, Giudice LC, Greene WC, Roan NR. HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread. 2020. PMID: 32452381


  34. Hsiao F, Frouard J, Gramatica A, Xie G, Telwatte S, Lee GQ, Roychoudhury P, Schwarzer R, Luo X, Yukl SA, Lee S, Hoh R, Deeks SG, Jones RB, Cavrois M, Greene WC, Roan NR. Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection. 2020. PMID: 32353080


  35. George AF, Jang KS, Nyegaard M, Neidleman J, Spitzer TL, Xie G, Chen JC, Herzig E, Laustsen A, Marques de Menezes EG, Houshdaran S, Pilcher CD, Norris PJ, Jakobsen MR, Greene WC, Giudice LC, Roan NR. Seminal plasma promotes decidualization of endometrial stromal fibroblasts in vitro from women with and without inflammatory disorders in a manner dependent on interleukin-11 signaling. 2020. PMID: 32219408


  37. Luo X, Herzig E, Doitsh G, Grimmett ZW, Muñoz-Arias I, Greene WC. HIV-2 depletes CD4 T cells through pyroptosis despite Vpx-dependent degradation of SAMHD1. 2019. PMID: 31578293


  38. Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA. Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency. 2019. PMID: 31711503


  39. Herzig E, Kim KC, Packard TA, Vardi N, Schwarzer R, Gramatica A, Deeks SG, Williams SR, Landgraf K, Killeen N, Martin DW, Weinberger LS, Greene WC. Attacking Latent HIV with convertibleCAR-T Cells, a Highly Adaptable Killing Platform. 2019. PMID: 31668804


  40. Mainzer C, Packard T, Bordes S, Closs B, Greene WC, Elias PM, Uchida Y. Tissue microenvironment initiates an immune response to structural components of S. aureus. 2018. PMID: 30566255


  41. Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. 2018. PMID: 30300855


  42. Martin JW, Chen JC, Neidleman J, Tatsumi K, Hu J, Giudice LC, Greene WC, Roan NR. Potent and rapid activation of tropomyosin-receptor kinase A in endometrial stromal fibroblasts by seminal plasma. 2018. PMID: 29518187


  43. Battivelli E, Dahabieh MS, Abdel-Mohsen M, Svensson JP, Tojal Da Silva I, Cohn LB, Gramatica A, Deeks S, Greene WC, Pillai SK, Verdin E. Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4+ T Cells. 2018. PMID: 29714165


  44. Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR. Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells. Volume 20 of Issue 4. 2017. PMID: 28746881


  45. Roan NR, Sandi-Monroy N, Kohgadai N, Usmani SM, Hamil KG, Neidleman J, Montano M, Ständker L, Röcker A, Cavrois M, Rosen J, Marson K, Smith JF, Pilcher CD, Gagsteiger F, Sakk O, O'Rand M, Lishko PV, Kirchhoff F, Münch J, Greene WC. Semen amyloids participate in spermatozoa selection and clearance. Volume 6. 2017. PMID: 28653619


  46. Boehm D, Jeng M, Camus G, Gramatica A, Schwarzer R, Johnson JR, Hull PA, Montano M, Sakane N, Pagans S, Godin R, Deeks SG, Krogan NJ, Greene WC, Ott M. SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency. Volume 21 of Issue 5. 2017. PMID: 28494238


  47. Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Volume 544 of Issue 7648. 2017. PMID: 28329768


  48. Neidleman JA, Chen JC, Kohgadai N, Müller JA, Laustsen A, Thavachelvam K, Jang KS, Stürzel CM, Jones JJ, Ochsenbauer C, Chitre A, Somsouk M, Garcia MM, Smith JF, Greenblatt RM, Münch J, Jakobsen MR, Giudice LC, Greene WC, Roan NR. Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells. Volume 13 of Issue 2. 2017. PMID: 28207890


  49. Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, Krogan NJ, Siliciano RF, Weissman JS, Verdin E. The mTOR Complex Controls HIV Latency. Volume 20 of Issue 6. 2016. PMID: 27978436


  50. Li P, Kaiser P, Lampiris HW, Kim P, Yukl SA, Havlir DV, Greene WC, Wong JK. Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation. Volume 22 of Issue 7. 2016. PMID: 27294875


  51. LoRicco JG, Xu CS, Neidleman J, Bergkvist M, Greene WC, Roan NR, Makhatadze GI. Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection. Volume 291 of Issue 27. 2016. PMID: 27226574


  52. Doitsh G, Greene WC. Dissecting How CD4 T Cells Are Lost During HIV Infection. Volume 19 of Issue 3. 2016. PMID: 26962940


  53. Muñoz-Arias I, Doitsh G, Yang Z, Sowinski S, Ruelas D, Greene WC. Blood-Derived CD4 T Cells Naturally Resist Pyroptosis during Abortive HIV-1 Infection. Volume 18 of Issue 4. 2015. PMID: 26468749


  54. Galloway NL, Doitsh G, Monroe KM, Yang Z, Muñoz-Arias I, Levy DN, Greene WC. Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells. Volume 12 of Issue 10. 2015. PMID: 26321639


  55. Ruelas DS, Chan JK, Oh E, Heidersbach AJ, Hebbeler AM, Chavez L, Verdin E, Rape M, Greene WC. MicroRNA-155 Reinforces HIV Latency. Volume 290 of Issue 22. 2015. PMID: 25873391


  56. Zirafi O, Kim KA, Roan NR, Kluge SF, Müller JA, Jiang S, Mayer B, Greene WC, Kirchhoff F, Münch J. Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides. Volume 6 of Issue 262. 2014. PMID: 25391483


  57. Cavrois M, Neidleman J, Greene WC. HIV-1 Fusion Assay. Volume 4 of Issue 16. 2014. PMID: 27525294


  58. Yang Z, Greene WC. A new activity for SAMHD1 in HIV restriction. Volume 20 of Issue 8. 2014. PMID: 25100520


  59. Roan NR, Liu H, Usmani SM, Neidleman J, Müller JA, Avila-Herrera A, Gawanbacht A, Zirafi O, Chu S, Dong M, Kumar ST, Smith JF, Pollard KS, Fändrich M, Kirchhoff F, Münch J, Witkowska HE, Greene WC. Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection. Volume 88 of Issue 13. 2014. PMID: 24741080


  60. Roan NR, Chu S, Liu H, Neidleman J, Witkowska HE, Greene WC. Interaction of fibronectin with semen amyloids synergistically enhances HIV infection. Volume 210 of Issue 7. 2014. PMID: 24719472


  61. Usmani SM, Zirafi O, Müller JA, Sandi-Monroy NL, Yadav JK, Meier C, Weil T, Roan NR, Greene WC, Walther P, Nilsson KP, Hammarström P, Wetzel R, Pilcher CD, Gagsteiger F, Fändrich M, Kirchhoff F, Münch J. Direct visualization of HIV-enhancing endogenous amyloid fibrils in human semen. Volume 5. 2014. PMID: 24691351


  62. Chen JC, Johnson BA, Erikson DW, Piltonen TT, Barragan F, Chu S, Kohgadai N, Irwin JC, Greene WC, Giudice LC, Roan NR. Seminal plasma induces global transcriptomic changes associated with cell migration, proliferation and viability in endometrial epithelial cells and stromal fibroblasts. Volume 29 of Issue 6. 2014. PMID: 24626806


  63. Doitsh G, Galloway NL, Geng X, Yang Z, Monroe KM, Zepeda O, Hunt PW, Hatano H, Sowinski S, Muñoz-Arias I, Greene WC. Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection. Volume 505 of Issue 7484. 2014. PMID: 24356306


  64. Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, Singhania A, Soto PC, Terry VH, Verdin E, Woelk C, Wooden S, Xing S, Planelles V. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. Volume 9 of Issue 12. 2013. PMID: 24385908


  65. Monroe KM, Yang Z, Johnson JR, Geng X, Doitsh G, Krogan NJ, Greene WC. IFI16 DNA sensor is required for death of lymphoid CD4 T cells abortively infected with HIV. Volume 343 of Issue 6169. 2013. PMID: 24356113


  66. Cavrois M, Neidleman J, Santiago ML, Derdeyn CA, Hunter E, Greene WC. Enhanced fusion and virion incorporation for HIV-1 subtype C envelope glycoproteins with compact V1/V2 domains. Volume 88 of Issue 4. 2013. PMID: 24335304


  67. Greene WC. Solutions to global health challenges: no more Band-Aids. Volume 123 of Issue 11. 2013. PMID: 24177468


  68. Chan JK, Bhattacharyya D, Lassen KG, Ruelas D, Greene WC. Calcium/calcineurin synergizes with prostratin to promote NF-?B dependent activation of latent HIV. Volume 8 of Issue 10. 2013. PMID: 24204950


  69. Ruelas DS, Greene WC. An integrated overview of HIV-1 latency. Volume 155 of Issue 3. 2013. PMID: 24243012


  71. Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. Volume 9 of Issue 4. 2013. PMID: 23593007


  72. Webster B, Wissing S, Herker E, Ott M, Greene WC. Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis. Volume 87 of Issue 1. 2012. PMID: 23097449


  73. Roan NR, Cavrois M, Greene WC. [Role of semen-derived amyloid fibrils as facilitators of HIV infection]. Volume 28 of Issue 4. 2012. PMID: 22549858


  74. Chan JK, Greene WC. Dynamic roles for NF-?B in HTLV-I and HIV-1 retroviral pathogenesis. Volume 246 of Issue 1. 2012. PMID: 22435562


  75. Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Günthard HF, Wong JK. Role of retroviral restriction factors in the interferon-a-mediated suppression of HIV-1 in vivo. Volume 109 of Issue 8. 2012. PMID: 22315404


  76. Lassen KG, Hebbeler AM, Bhattacharyya D, Lobritz MA, Greene WC. A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs. Volume 7 of Issue 1. 2012. PMID: 22291913


  77. Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM. Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia. Volume 86 of Issue 5. 2011. PMID: 22205732


  78. Roan NR, Müller JA, Liu H, Chu S, Arnold F, Stürzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, Münch J, Greene WC. Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection. Volume 10 of Issue 6. 2011. PMID: 22177559


  79. Arnold F, Schnell J, Zirafi O, Stürzel C, Meier C, Weil T, Ständker L, Forssmann WG, Roan NR, Greene WC, Kirchhoff F, Münch J. Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection. Volume 86 of Issue 2. 2011. PMID: 22090109


  80. Wissing S, Muñoz-Lopez M, Macia A, Yang Z, Montano M, Collins W, Garcia-Perez JL, Moran JV, Greene WC. Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility. Volume 21 of Issue 1. 2011. PMID: 21989055


  81. Smith DS, Guo K, Barrett BS, Heilman KJ, Evans LH, Hasenkrug KJ, Greene WC, Santiago ML. Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response. Volume 7 of Issue 10. 2011. PMID: 21998583


  82. Siliciano RF, Greene WC. HIV latency. Volume 1 of Issue 1. 2011. PMID: 22229121


  83. Wissing S, Montano M, Garcia-Perez JL, Moran JV, Greene WC. Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells. Volume 286 of Issue 42. 2011. PMID: 21878639


  84. Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M. Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). Volume 7 of Issue 8. 2011. PMID: 21876670


  85. Chan JK, Greene WC. NF-?B/Rel: agonist and antagonist roles in HIV-1 latency. Volume 6 of Issue 1. 2011. PMID: 21242888


  86. Doitsh G, Cavrois M, Lassen KG, Zepeda O, Yang Z, Santiago ML, Hebbeler AM, Greene WC. Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue. Volume 143 of Issue 5. 2010. PMID: 21111238


  87. Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM. HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells. Volume 409 of Issue 2. 2010. PMID: 21056450


  88. Santiago ML, Smith DS, Barrett BS, Montano M, Benitez RL, Pelanda R, Hasenkrug KJ, Greene WC. Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor. Volume 85 of Issue 1. 2010. PMID: 20980520


  89. Lassen KG, Wissing S, Lobritz MA, Santiago M, Greene WC. Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif. Volume 285 of Issue 38. 2010. PMID: 20624919


  90. Kim KA, Yolamanova M, Zirafi O, Roan NR, Staendker L, Forssmann WG, Burgener A, Dejucq-Rainsford N, Hahn BH, Shaw GM, Greene WC, Kirchhoff F, Münch J. Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI. Volume 7. 2010. PMID: 20573198


  91. Santiago ML, Benitez RL, Montano M, Hasenkrug KJ, Greene WC. Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo. Volume 185 of Issue 2. 2010. PMID: 20566830


  92. Wissing S, Galloway NL, Greene WC. HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors. Volume 31 of Issue 5. 2010. PMID: 20538015


  93. Cavrois M, Neidleman J, Galloway N, Derdeyn CA, Hunter E, Greene WC. Measuring HIV fusion mediated by envelopes from primary viral isolates. Volume 53 of Issue 1. 2010. PMID: 20554044


  94. Roan NR, Sowinski S, Münch J, Kirchhoff F, Greene WC. Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection). Volume 285 of Issue 3. 2009. PMID: 19897482


  95. Chiu YL, Greene WC. APOBEC3G: an intracellular centurion. Volume 364 of Issue 1517. 2009. PMID: 19008196


  96. Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ. The challenge of finding a cure for HIV infection. Volume 323 of Issue 5919. 2009. PMID: 19265012


  97. Michel N, Goffinet C, Ganter K, Allespach I, Kewalramani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT. Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo. Volume 6. 2009. PMID: 19144136


  98. Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, Bukrinsky M, Burny A, Caruso A, Cassol S, Chandra P, Ceccherini-Nelli L, Chieco-Bianchi L, Clerici M, Colombini-Hatch S, de Giuli Morghen C, de Maria A, de Rossi A, Dierich M, Della-Favera R, Dolei A, Douek D, Erfle V, Felber B, Fiorentini S, Franchini G, Gershoni JM, Gotch F, Green P, Greene WC, Hall W, Haseltine W, Jacobson S, Kallings LO, Kalyanaraman VS, Katinger H, Khalili K, Klein G, Klein E, Klotman M, Klotman P, Kotler M, Kurth R, Lafeuillade A, La Placa M, Lewis J, Lillo F, Lisziewicz J, Lomonico A, Lopalco L, Lori F, Lusso P, Macchi B, Malim M, Margolis L, Markham PD, McClure M, Miller N, Mingari MC, Moretta L, Noonan D, O'Brien S, Okamoto T, Pal R, Palese P, Panet A, Pantaleo G, Pavlakis G, Pistello M, Plotkin S, Poli G, Pomerantz R, Radaelli A, Robertguroff M, Roederer M, Sarngadharan MG, Schols D, Secchiero P, Shearer G, Siccardi A, Stevenson M, Svoboda J, Tartaglia J, Torelli G, Tornesello ML, Tschachler E, Vaccarezza M, Vallbracht A, van Lunzen J, Varnier O, Vicenzi E, von Melchner H, Witz I, Zagury D, Zagury JF, Zauli G, Zipeto D. Unsung hero Robert C. Gallo. Volume 323 of Issue 5911. 2009. PMID: 19131607


  99. LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, Strebel K, Wain-Hobson S, Yu XF, Yuhki N, Harris RS. Guidelines for naming nonprimate APOBEC3 genes and proteins. Volume 83 of Issue 2. 2008. PMID: 18987154


  100. Roan NR, Münch J, Arhel N, Mothes W, Neidleman J, Kobayashi A, Smith-McCune K, Kirchhoff F, Greene WC. The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection. Volume 83 of Issue 1. 2008. PMID: 18945786


  101. Greene WC, Debyser Z, Ikeda Y, Freed EO, Stephens E, Yonemoto W, Buckheit RW, Esté JA, Cihlar T. Novel targets for HIV therapy. Volume 80 of Issue 3. 2008. PMID: 18789977


  102. Santiago ML, Montano M, Benitez R, Messer RJ, Yonemoto W, Chesebro B, Hasenkrug KJ, Greene WC. Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection. Volume 321 of Issue 5894. 2008. PMID: 18772436


  103. Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC. HIV vaccine research: the way forward. Volume 321 of Issue 5888. 2008. PMID: 18653883


  104. Cavrois M, Neidleman J, Greene WC. The achilles heel of the trojan horse model of HIV-1 trans-infection. Volume 4 of Issue 6. 2008. PMID: 18584030


  105. Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M. Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation. Volume 3 of Issue 3. 2008. PMID: 18329615


  107. Roan NR, Greene WC. A seminal finding for understanding HIV transmission. Volume 131 of Issue 6. 2007. PMID: 18083095


  108. Greene WC. A history of AIDS: looking back to see ahead. Volume 37 Suppl 1. 2007. PMID: 17972351


  109. Goffinet C, Michel N, Allespach I, Tervo HM, Hermann V, Kräusslich HG, Greene WC, Keppler OT. Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression. Volume 4. 2007. PMID: 17655755


  110. Williams SA, Greene WC. Regulation of HIV-1 latency by T-cell activation. Volume 39 of Issue 1. 2007. PMID: 17643313


  111. Ellery PJ, Tippett E, Chiu YL, Paukovics G, Cameron PU, Solomon A, Lewin SR, Gorry PR, Jaworowski A, Greene WC, Sonza S, Crowe SM. The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. Volume 178 of Issue 10. 2007. PMID: 17475889


  112. Williams SA, Kwon H, Chen LF, Greene WC. Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1. Volume 81 of Issue 11. 2007. PMID: 17376917


  113. Soros VB, Greene WC. APOBEC3G and HIV-1: strike and counterstrike. Volume 4 of Issue 1. 2007. PMID: 17338854


  115. Cavrois M, Neidleman J, Kreisberg JF, Greene WC. In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions. Volume 3 of Issue 1. 2007. PMID: 17238285


  116. Stopak KS, Chiu YL, Kropp J, Grant RM, Greene WC. Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells. Volume 282 of Issue 6. 2006. PMID: 17110377


  117. Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA. A plea for justice for jailed medical workers. Volume 314 of Issue 5801. 2006. PMID: 17062652


  118. Chiu YL, Witkowska HE, Hall SC, Santiago M, Soros VB, Esnault C, Heidmann T, Greene WC. High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition. Volume 103 of Issue 42. 2006. PMID: 17030807


  119. O'Mahony A, Raber J, Montano M, Foehr E, Han V, Lu SM, Kwon H, LeFevour A, Chakraborty-Sett S, Greene WC. NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity. Volume 26 of Issue 19. 2006. PMID: 16980629


  120. Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V. Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. Volume 80 of Issue 21. 2006. PMID: 16956949


  121. Soros VB, Greene WC. APOBEC3G and HIV-1: strike and counterstrike. Volume 8 of Issue 4. 2006. PMID: 16822376


  122. Chiu YL, Greene WC. Multifaceted antiviral actions of APOBEC3 cytidine deaminases. Volume 27 of Issue 6. 2006. PMID: 16678488


  124. Chandrasekar B, Mummidi S, Mahimainathan L, Patel DN, Bailey SR, Imam SZ, Greene WC, Valente AJ. Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin. Volume 281 of Issue 22. 2006. PMID: 16554298


  125. Cavrois M, Neidleman J, Kreisberg JF, Fenard D, Callebaut C, Greene WC. Human immunodeficiency virus fusion to dendritic cells declines as cells mature. Volume 80 of Issue 4. 2006. PMID: 16439555


  126. Chiu YL, Greene WC. APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle. Volume 281 of Issue 13. 2005. PMID: 16407183


  127. Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. Volume 25 of Issue 1. 2005. PMID: 16319923


  128. Fenard D, Yonemoto W, de Noronha C, Cavrois M, Williams SA, Greene WC. Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement. Volume 175 of Issue 9. 2005. PMID: 16237100


  129. Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L, Greene WC. NF-kappaB RelA phosphorylation regulates RelA acetylation. Volume 25 of Issue 18. 2005. PMID: 16135789


  130. Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher DW, Greene WC. Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax. Volume 280 of Issue 42. 2005. PMID: 16105841


  131. Chen LF, Greene WC. Assessing acetylation of NF-kappaB. Volume 36 of Issue 4. 2005. PMID: 16111893


  132. Williams SA, Greene WC. Host factors regulating post-integration latency of HIV. Volume 13 of Issue 4. 2005. PMID: 15817380


  133. Stopak K, Greene WC. Protecting APOBEC3G: a potential new target for HIV drug discovery. Volume 6 of Issue 2. 2005. PMID: 15751736


  134. Keppler OT, Allespach I, Schüller L, Fenard D, Greene WC, Fackler OT. Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef. Volume 79 of Issue 3. 2005. PMID: 15650191


  136. Cavrois M, Neidleman J, Yonemoto W, Fenard D, Greene WC. HIV-1 virion fusion assay: uncoating not required and no effect of Nef on fusion. Volume 328 of Issue 1. 2004. PMID: 15380356


  137. Greene WC. The brightening future of HIV therapeutics. Volume 5 of Issue 9. 2004. PMID: 15334078


  138. Greene WC. Redistricting the retroviral restriction factors. Volume 10 of Issue 8. 2004. PMID: 15286773


  139. Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC. Prostratin antagonizes HIV latency by activating NF-kappaB. Volume 279 of Issue 40. 2004. PMID: 15284245


  140. Chen LF, Greene WC. Shaping the nuclear action of NF-kappaB. Volume 5 of Issue 5. 2004. PMID: 15122352


  141. Bohuslav J, Chen LF, Kwon H, Mu Y, Greene WC. p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1. Volume 279 of Issue 25. 2004. PMID: 15073170


  142. O'Mahony AM, Montano M, Van Beneden K, Chen LF, Greene WC. Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65. Volume 279 of Issue 18. 2004. PMID: 14963024


  143. Schaeffer E, Soros VB, Greene WC. Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes. Volume 78 of Issue 3. 2004. PMID: 14722292


  144. Cavrois M, Neidleman J, Bigos M, Greene WC. Fluorescence resonance energy transfer-based HIV-1 virion fusion assay. Volume 263. 2004. PMID: 14976375


  145. Greene WC. How resting T cells deMURR HIV infection. Volume 5 of Issue 1. 2004. PMID: 14699403


  146. Greene WC, Chen LF. Regulation of NF-kappaB action by reversible acetylation. Volume 259. 2004. PMID: 15171256


  147. Stopak K, de Noronha C, Yonemoto W, Greene WC. HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Volume 12 of Issue 3. 2003. PMID: 14527406


  149. Zander K, Sherman MP, Tessmer U, Bruns K, Wray V, Prechtel AT, Schubert E, Henklein P, Luban J, Neidleman J, Greene WC, Schubert U. Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression. Volume 278 of Issue 44. 2003. PMID: 12881522


  150. Sherman MP, de Noronha CM, Eckstein LA, Hataye J, Mundt P, Williams SA, Neidleman JA, Goldsmith MA, Greene WC. Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages. Volume 77 of Issue 13. 2003. PMID: 12805458


  151. Stoddart CA, Geleziunas R, Ferrell S, Linquist-Stepps V, Moreno ME, Bare C, Xu W, Yonemoto W, Bresnahan PA, McCune JM, Greene WC. Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis. Volume 77 of Issue 3. 2003. PMID: 12525647


  153. Sherman MP, Schubert U, Williams SA, de Noronha CM, Kreisberg JF, Henklein P, Greene WC. HIV-1 Vpr displays natural protein-transducing properties: implications for viral pathogenesis. 2002. PMID: 12429519


  155. Sherman MP, De Noronha CM, Williams SA, Greene WC. Insights into the biology of HIV-1 viral protein R. 2002. PMID: 12396611


  156. Greene WC, Peterlin BM. Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy. Volume 8 of Issue 7. 2002. PMID: 12091904


  157. Sherman MP, Greene WC. Slipping through the door: HIV entry into the nucleus. 2002. PMID: 11825777


  158. Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CM, Greene WC, Goldsmith MA. HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. 2001. PMID: 11714748


  159. de Noronha CM, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC. Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr. 2001. PMID: 11691994


  160. . Duration of nuclear NF-kappaB action regulated by reversible acetylation. Volume 293 of Issue 5535. 2001. PMID: 11533489


  161. Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Volume 410 of Issue 6830. 2001. PMID: 11298454


  163. Sherman MP, de Noronha CM, Heusch MI, Greene S, Greene WC. Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr. 2001. PMID: 11152524


  164. Foehr ED, Bohuslav J, Chen LF, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC. The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis. 2000. PMID: 10980190


  165. Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC. NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells. 2000. PMID: 11027214


  166. Henklein P, Bruns K, Sherman MP, Tessmer U, Licha K, Kopp J, de Noronha CM, Greene WC, Wray V, Schubert U. Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest. Volume 275 of Issue 41. 2000. PMID: 10903315


  171. Heusch M, Lin L, Geleziunas R, Greene WC. The generation of nfkb2 p52: mechanism and efficiency. 1999. PMID: 10597218


  174. Jenkins Y, McEntee M, Weis K, Greene WC. Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways. 1998. PMID: 9817747


  175. Bresnahan PA, Yonemoto W, Ferrell S, Williams-Herman D, Geleziunas R, Greene WC. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. 1998. PMID: 9811606


  176. Lin X, Mu Y, Cunningham ET, Marcu KB, Geleziunas R, Greene WC. Molecular determinants of NF-kappaB-inducing kinase action. 1998. PMID: 9742107


  177. Liegler TJ, Yonemoto W, Elbeik T, Vittinghoff E, Buchbinder SP, Greene WC. Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors. 1998. PMID: 9728534


  178. Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC. Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases. 1998. PMID: 9710600


  179. Lin L, DeMartino GN, Greene WC. Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome. 1998. PMID: 9529257


  180. Liu KD, Gaffen SL, Goldsmith MA, Greene WC. Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation. Volume 7 of Issue 11. 1997. PMID: 9382798


  182. Miller MD, Warmerdam MT, Ferrell SS, Benitez R, Greene WC. Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity. Volume 234 of Issue 2. 1997. PMID: 9268152


  184. Tie F, Adya N, Greene WC, Giam CZ. Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat. Volume 70 of Issue 12. 1996. PMID: 8970957


  185. Geleziunas R, Miller MD, Greene WC. Unraveling the function of HIV type 1 Nef. 1996. PMID: 8947291


  186. Shapiro VS, Mollenauer MN, Greene WC, Weiss A. c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1. 1996. PMID: 8920856


  187. Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA. Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity. Volume 271 of Issue 35. 1996. PMID: 8702919


  188. Kim JH, McLinden RJ, Mosca JD, Vahey MT, Greene WC, Redfield RR. Inhibition of HIV replication by sense and antisense rev response elements in HIV-based retroviral vectors. Volume 12 of Issue 4. 1996. PMID: 8673542


  190. Greene WC. Denying HIV safe haven. Volume 334 of Issue 19. 1996. PMID: 8606724


  191. Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT. Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3. Volume 148 of Issue 5. 1996. PMID: 8623933


  192. Miller MD, Greene WC. Is the Nef protein of HIV-1 required for pathogenesis? 1996. PMID: 8727595


  193. Sun S, Elwood J, Greene WC. Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation. Volume 16 of Issue 3. 1996. PMID: 8622650


  194. Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA. The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes. Volume 93 of Issue 1. 1996. PMID: 8552611


  195. Béraud C, Greene WC. Interaction of HTLV-I Tax with the human proteasome: implications for NF-kappa B induction. Volume 13 Suppl 1. 1996. PMID: 8797708


  196. Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC. Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association. Volume 270 of Issue 48. 1995. PMID: 7499411


  197. Greene WC. Predicting progression to AIDS. Volume 123 of Issue 9. 1995. PMID: 7574230


  199. Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC. Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. 1995. PMID: 7665592


  200. Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC. Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. 1995. PMID: 7543676


  201. Goldsmith MA, Warmerdam MT, Atchison RE, Miller MD, Greene WC. Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. 1995. PMID: 7769669


  205. Miller MD, Feinberg MB, Greene WC. The HIV-1 nef gene acts as a positive viral infectivity factor. Volume 2 of Issue 8. 1994. PMID: 7981973


  210. Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB. The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. Volume 179 of Issue 1. 1994. PMID: 8270859


  212. Stein B, Baldwin AS, Ballard DW, Greene WC, Angel P, Herrlich P. Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function. Volume 12 of Issue 10. 1993. PMID: 8404856


  213. Greene WC. AIDS and the immune system. Volume 269 of Issue 3. 1993. PMID: 8211096


  221. Mills GB, Arima N, May C, Hill M, Schmandt R, Li J, Miyamoto NG, Greene WC. Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells. Volume 4 of Issue 11. 1992. PMID: 1472476


  223. Walker WH, Stein B, Ganchi PA, Hoffman JA, Kaufman PA, Ballard DW, Hannink M, Greene WC. The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation. Volume 66 of Issue 8. 1992. PMID: 1321284


  224. Weichselbraun I, Berger J, Dobrovnik M, Bogerd H, Grassmann R, Greene WC, Hauber J, Böhnlein E. Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance. Volume 66 of Issue 7. 1992. PMID: 1602559


  225. Arima N, Kuziel WA, Grdina TA, Greene WC. IL-2-induced signal transduction involves the activation of nuclear NF-kappa B expression. Volume 149 of Issue 1. 1992. PMID: 1607664


  227. Smith MR, Greene WC. Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein. Volume 187 of Issue 1. 1992. PMID: 1736534


  228. Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B, Greene WC. The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Volume 89 of Issue 5. 1992. PMID: 1542686


  230. Molitor JA, Ballard DW, Greene WC. Kappa B-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation. Volume 3 of Issue 10. 1991. PMID: 1768652


  233. Lee JH, Li YC, Doerre S, Sista P, Ballard DW, Greene WC, Franza BR. A member of the set of kappa B binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene. Volume 6 of Issue 4. 1991. PMID: 2030915


  234. Hémar A, Cereghini S, Cornet V, Blank V, Israël A, Greene WC, Dautry-Varsat A. Kappa B binding proteins are constitutively expressed in an IL-2 autocrine human T cell line. Volume 146 of Issue 7. 1991. PMID: 2005404


  235. Smith MR, Greene WC. Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia. Volume 87 of Issue 3. 1991. PMID: 1999493


  236. Ahmed YF, Gilmartin GM, Hanly SM, Nevins JR, Greene WC. The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation. Volume 64 of Issue 4. 1991. PMID: 1671761


  237. Greene WC. The molecular biology of human immunodeficiency virus type 1 infection. Volume 324 of Issue 5. 1991. PMID: 1986289


  238. Smith MR, Greene WC. Functional analyses of the type I human T-cell leukemia virus tax gene product. Volume 104. 1991. PMID: 1845158


  239. Kim JH, Kaufman PA, Hanly SM, Rimsky LT, Greene WC. Rex transregulation of human T-cell leukemia virus type II gene expression. Volume 65 of Issue 1. 1991. PMID: 1985205


  240. Molitor JA, Walker WH, Doerre S, Ballard DW, Greene WC. NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells. Volume 87 of Issue 24. 1990. PMID: 2263603


  241. Ballard DW, Walker WH, Doerre S, Sista P, Molitor JA, Dixon EP, Peffer NJ, Hannink M, Greene WC. The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function. Volume 63 of Issue 4. 1990. PMID: 2225078


  242. Smith MR, Greene WC. Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes. Volume 4 of Issue 11. 1990. PMID: 2276622


  243. Cullen BR, Greene WC. Functions of the auxiliary gene products of the human immunodeficiency virus type 1. Volume 178 of Issue 1. 1990. PMID: 2202146


  244. Rubin LA, Galli F, Greene WC, Nelson DL, Jay G. The molecular basis for the generation of the human soluble interleukin 2 receptor. Volume 2 of Issue 5. 1990. PMID: 2103332


  245. Kuziel WA, Greene WC. Interleukin-2 and the IL-2 receptor: new insights into structure and function. Volume 94 of Issue 6 Suppl. 1990. PMID: 1693645


  246. Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC. Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action. Volume 4 of Issue 6. 1990. PMID: 2116986


  248. Mills GB, May C, McGill M, Fung M, Baker M, Sutherland R, Greene WC. Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated. Volume 265 of Issue 6. 1990. PMID: 2303462


  249. Greene WC. Regulation of HIV-1 gene expression. Volume 8. 1990. PMID: 2188670


  250. Pomerantz JL, Mauxion F, Yoshida M, Greene WC, Sen R. A second sequence element located 3' to the NF-kappa B-binding site regulates IL-2 receptor-alpha gene induction. Volume 143 of Issue 12. 1989. PMID: 2687377


  251. Hammes SR, Dixon EP, Malim MH, Cullen BR, Greene WC. Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor. Volume 86 of Issue 23. 1989. PMID: 2687884


  253. Rimsky L, Dodon MD, Dixon EP, Greene WC. Trans-dominant inactivation of HTLV-I and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator. Volume 341 of Issue 6241. 1989. PMID: 2677743


  254. Ballard DW, Böhnlein E, Hoffman JA, Bogerd HP, Dixon EP, Franza BR, Greene WC. Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer. Volume 1 of Issue 1. 1989. PMID: 2518691


  255. Hanly SM, Rimsky LT, Malim MH, Kim JH, Hauber J, Duc Dodon M, Le SY, Maizel JV, Cullen BR, Greene WC. Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements. Volume 3 of Issue 10. 1989. PMID: 2482226


  256. Cullen BR, Greene WC. Regulatory pathways governing HIV-1 replication. Volume 58 of Issue 3. 1989. PMID: 2569361


  257. Greene WC, Böhnlein E, Ballard DW. HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises. Volume 10 of Issue 8. 1989. PMID: 2679647


  258. Böhnlein E, Ballard DW, Bogerd H, Peffer NJ, Lowenthal JW, Greene WC. Induction of interleukin-2 receptor-alpha gene expression is regulated by post-translational activation of kappa B specific DNA binding proteins. Volume 264 of Issue 15. 1989. PMID: 2785992


  259. Lowenthal JW, Ballard DW, Bogerd H, Böhnlein E, Greene WC. Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins. Volume 142 of Issue 9. 1989. PMID: 2785134


  260. Hoyos B, Ballard DW, Böhnlein E, Siekevitz M, Greene WC. Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression. Volume 244 of Issue 4903. 1989. PMID: 2497518


  261. Böhnlein E, Siekevitz M, Ballard DW, Lowenthal JW, Rimsky L, Bogérd H, Hoffman J, Wano Y, Franza BR, Greene WC. Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins. Volume 63 of Issue 4. 1989. PMID: 2784507


  263. Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Ballard DW, Greene WC. HIV-1, HTLV-I and the interleukin-2 receptor: insights into transcriptional control. Volume 32. 1989. PMID: 2625257


  264. Wano Y, Feinberg M, Hosking JB, Bogerd H, Greene WC. Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth. Volume 85 of Issue 24. 1988. PMID: 3059351


  266. Rimsky L, Hauber J, Dukovich M, Malim MH, Langlois A, Cullen BR, Greene WC. Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein. Volume 335 of Issue 6192. 1988. PMID: 3262832


  267. Collins L, Tsien WH, Seals C, Hakimi J, Weber D, Bailon P, Hoskings J, Greene WC, Toome V, Ju G. Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor. Volume 85 of Issue 20. 1988. PMID: 3051003


  268. Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Greene WC. HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene. Volume 241 of Issue 4873. 1988. PMID: 2843985


  269. Froussard P, Chastagner P, Sommé G, Abadie A, Greene W, Thèze J, Longacre S. p55 IL-2 receptor mRNA precursors in murine T lymphocyte nuclei. Volume 141 of Issue 4. 1988. PMID: 3135330


  270. Böhnlein E, Lowenthal JW, Siekevitz M, Ballard DW, Franza BR, Greene WC. The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Volume 53 of Issue 5. 1988. PMID: 2836068


  272. Cullen BR, Podlaski FJ, Peffer NJ, Hosking JB, Greene WC. Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor. Volume 263 of Issue 10. 1988. PMID: 2832410


  273. Greene WC. Sarcoidosis and interleukin-2 receptors. Volume 137 of Issue 4. 1988. PMID: 2833139


  276. Wano Y, Dukovich M, Kehrl JH, Greene WC. In: Smith KA (Ed.), Interleukin 2 1988. PMID:


  277. Greene WC, Wano YJ, Dukovich M. New insights into the structure of high-affinity interleukin-2 receptors. Volume 44. 1988. PMID: 3064206


  278. Kehrl JH, Dukovich M, Whalen G, Katz P, Fauci AS, Greene WC. Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells. Volume 81 of Issue 1. 1988. PMID: 2826541


  279. Greene WC, Böhnlein E, Siekevitz M, Franza BR, Lowenthal J. The human interleukin-2 receptor. Recent studies of structure and regulation. Volume 546. 1988. PMID: 3073691


  280. Siekevitz M, Josephs SF, Dukovich M, Peffer N, Wong-Staal F, Greene WC. Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I. Volume 238 of Issue 4833. 1987. PMID: 2825351


  282. Rubin LA, Hoekzema GS, Nelson DL, Greene WC, Jay G. Reconstitution of a functional interleukin 2 receptor in a nonlymphoid cell. Volume 139 of Issue 7. 1987. PMID: 2821112


  283. Bich-Thuy LT, Dukovich M, Peffer NJ, Fauci AS, Kehrl JH, Greene WC. Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein. Volume 139 of Issue 5. 1987. PMID: 3040856


  284. Wano Y, Hattori T, Matsuoka M, Takatsuki K, Chua AO, Gubler U, Greene WC. Interleukin 1 gene expression in adult T cell leukemia. Volume 80 of Issue 3. 1987. PMID: 2887587


  286. Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC. Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I. Volume 84 of Issue 15. 1987. PMID: 3037548


  288. Holter W, Goldman CK, Casabo L, Nelson DL, Greene WC, Waldmann TA. Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes. Volume 138 of Issue 9. 1987. PMID: 3106493


  289. Bernard O, Fazekas de St Groth B, Ullrich A, Green W, Schlessinger J. High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule. Volume 84 of Issue 8. 1987. PMID: 3104909


  290. Robb RJ, Rusk CM, Yodoi J, Greene WC. Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors. Volume 84 of Issue 7. 1987. PMID: 3031660


  292. Wano Y, Cullen BR, Svetlik PA, Peffer NJ, Greene WC. Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector. Volume 4 of Issue 2. 1987. PMID: 3114593


  293. Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. Trans-activator gene of HTLV-II: interpretation. Volume 235 of Issue 4792. 1987. PMID: 3029865


  295. Greene WC, Leonard WJ. Human interleukin 2 receptor (Tac antigen). Volume 150. 1987. PMID: 3123879


  296. Greene WC, Leonard WJ, Wano Y, Sodroski JG, Rosen CA, Haseltine WA. In: Pruzanki W, Seligmann M (Eds.), Clinical Immunology 1987. PMID:


  298. Greene WC. Int. J. Immunother. III 1987. PMID:


  299. Greene WC. Proceedings of the AACR 1987 1987. PMID:


  300. Chanda PK, Chen GF, Baine Y, Leonard WJ, Greene WC, Chang TW, Chang NT. Expression of human interleukin-2 receptor cDNA in E. coli. Volume 141 of Issue 2. 1986. PMID: 3026392


  301. Neckers LM, Bauer S, McGlennen RC, Trepel JB, Rao K, Greene WC. Diltiazem inhibits transferrin receptor expression and causes G1 arrest in normal and neoplastic T cells. Volume 6 of Issue 12. 1986. PMID: 2432398


  303. Greene WC, Depper JM, Krönke M, Leonard WJ. The human interleukin-2 receptor: analysis of structure and function. Volume 92. 1986. PMID: 3091481


  305. Treiger BF, Leonard WJ, Svetlik P, Rubin LA, Nelson DL, Greene WC. A secreted form of the human interleukin 2 receptor encoded by an "anchor minus" cDNA. Volume 136 of Issue 11. 1986. PMID: 3084654


  306. Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA. Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression. Volume 232 of Issue 4752. 1986. PMID: 3010456


  307. Weissman AM, Harford JB, Svetlik PB, Leonard WL, Depper JM, Waldmann TA, Greene WC, Klausner RD. Only high-affinity receptors for interleukin 2 mediate internalization of ligand. Volume 83 of Issue 5. 1986. PMID: 3081898


  308. Greene WC, Leonard WJ, Depper JM. Growth of human T lymphocytes: an analysis of interleukin 2 and its cellular receptor. Volume 14. 1986. PMID: 2418464


  313. Greene WC, Leonard WJ. The human interleukin-2 receptor. Volume 4. 1986. PMID: 3011033


  314. Greene WC, Depper JM, Krönke M, Leonard WJ. The human interleukin-2 receptor: role in normal T-cell growth and association with HTLV-I-induced T-cell leukemia. Volume 51 Pt 2. 1986. PMID: 2884072


  315. Leonard WJ, Depper JM, Kanehisa M, Krönke M, Peffer NJ, Svetlik PB, Sullivan M, Greene WC. Structure of the human interleukin-2 receptor gene. Volume 230 of Issue 4726. 1985. PMID: 2996141


  317. Waldmann TA, Longo DL, Leonard WJ, Depper JM, Thompson CB, Krönke M, Goldman CK, Sharrow S, Bongiovanni K, Greene WC. Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia. Volume 45 of Issue 9 Suppl. 1985. PMID: 2990687


  318. Leonard WJ, Krönke M, Peffer NJ, Depper JM, Greene WC. Interleukin 2 receptor gene expression in normal human T lymphocytes. Volume 82 of Issue 18. 1985. PMID: 3929255


  319. Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA. Isolation and expression of complementary DNAs encoding the human interleukin 2 receptor. Volume 45 of Issue 9 Suppl. 1985. PMID: 2990688


  320. Lane HC, Depper JM, Greene WC, Whalen G, Waldmann TA, Fauci AS. Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition. Volume 313 of Issue 2. 1985. PMID: 2582258


  321. Greene WC, Robb RJ, Svetlik PB, Rusk CM, Depper JM, Leonard WJ. Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells. Volume 162 of Issue 1. 1985. PMID: 2989411


  322. Leonard WJ, Donlon TA, Lebo RV, Greene WC. Localization of the gene encoding the human interleukin-2 receptor on chromosome 10. Volume 228 of Issue 4707. 1985. PMID: 3925551


  323. Krönke M, Leonard WJ, Depper JM, Greene WC. Deregulation of interleukin-2 receptor gene expression in HTLV-I-induced adult T-cell leukemia. Volume 228 of Issue 4704. 1985. PMID: 2988127


  324. Krönke M, Depper JM, Leonard WJ, Vitetta ES, Waldmann TA, Greene WC. Adult T cell leukemia: a potential target for ricin A chain immunotoxins. Volume 65 of Issue 6. 1985. PMID: 2986744


  325. Depper JM, Leonard WJ, Drogula C, Krönke M, Waldmann TA, Greene WC. Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene. Volume 82 of Issue 12. 1985. PMID: 2987968


  326. Miller J, Malek TR, Leonard WJ, Greene WC, Shevach EM, Germain RN. Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA. Volume 134 of Issue 6. 1985. PMID: 3921620


  327. Krönke M, Leonard WJ, Depper JM, Greene WC. Sequential expression of genes involved in human T lymphocyte growth and differentiation. Volume 161 of Issue 6. 1985. PMID: 2989408


  329. Depper JM, Leonard WJ, Drogula CL, Krönke M, Waldmann TA, Greene WC. Activators of protein kinase C and 5-azacytidine induce IL-2 receptor expression on human T lymphocytes. Volume 27 of Issue 3. 1985. PMID: 2580852


  330. Reed JC, Robb RJ, Greene WC, Nowell PC. Effect of wheat germ agglutinin on the interleukin pathway of human T lymphocyte activation. Volume 134 of Issue 1. 1985. PMID: 3917278


  331. Waldmann TA, Leonard WJ, Depper JM, Kronke M, Kozak R, Greene WC. In: Cancer Cells 3: Growth factors and transformation 1985. PMID:


  332. Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Bongiovani KF, Greene WC.. In: Feldman M (Ed.), Human T cell clones: An approach to immune regulation 1985. PMID:


  333. Leonard WJ, Depper JM, Crabtee GM, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC. In: Feldmann M, Mitchison NA (Eds.), Immune Regulation 1985. PMID:


  334. Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Leonard WJ. In: Pattengale PK, Lukes RJ, Taylor CR (Eds.), Lymphoproliferative Diseases: Pathogenesis, Diagnosis, and Therapy 1985. PMID:


  335. Waldmann TA, Leonard WJ, Depper JM, Kronke M, Goldman CK, Sharrow S, Greene WC. In: Pinchera A, Doria G, Dammacco F, Bargellesi A (Eds.), Monoclonal Antibodies 1984: Biological and Clinical Applications 1985. PMID:


  336. Kronke M, Depper JM, Leonard WJ, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC. In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines 1985. PMID:


  337. Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Kronke M, Svetlik P, Peffer NJ, Waldmann TA, Greene WC. In: Sorg C, Schimple A (Eds.), Cellular and molecular biology of lymphokines 1985. PMID:


  338. Depper JM, Leonard WJ, Kronke M, Waldmann TA, Greene WC. In: Sorg P, Schimple A (Eds.), Cellular and molecular biology of lymphokines 1985. PMID:


  339. Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA. Molecular cloning of cDNA for the human interleukin-2 receptor. Volume 29. 1985. PMID: 2993133


  341. Greene WC, Depper JM, Krönke M, Leonard WJ. The human interleukin-2 receptor. Volume 3. 1985. PMID: 3938983


  342. Korsmeyer SJ, Greene WC, Waldmann TA. Cellular origin of hairy cell leukemia: malignant B cells that express receptors for T cell growth factor. Volume 11 of Issue 4. 1984. PMID: 6438801


  343. Depper JM, Leonard WJ, Krönke M, Noguchi PD, Cunningham RE, Waldmann TA, Greene WC. Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen. Volume 133 of Issue 6. 1984. PMID: 6092466


  344. Waldmann TA, Goldman CK, Robb RJ, Depper JM, Leonard WJ, Sharrow SO, Bongiovanni KF, Korsmeyer SJ, Greene WC. Expression of interleukin 2 receptors on activated human B cells. Volume 160 of Issue 5. 1984. PMID: 6092511


  345. Depper JM, Leonard WJ, Krönke M, Waldmann TA, Greene WC. Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells. Volume 133 of Issue 4. 1984. PMID: 6088625


  346. Robb RJ, Greene WC, Rusk CM. Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen. Volume 160 of Issue 4. 1984. PMID: 6090574


  347. Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik PB, Peffer NJ, Waldmann TA. Molecular cloning and expression of cDNAs for the human interleukin-2 receptor. Volume 311 of Issue 5987. 1984. PMID: 6090948


  348. Krönke M, Leonard WJ, Depper JM, Arya SK, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC. Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription. Volume 81 of Issue 16. 1984. PMID: 6332315


  349. Greene WC, Robb RJ, Depper JM, Leonard WJ, Drogula C, Svetlik PB, Wong-Staal F, Gallo RC, Waldmann TA. Phorbol diester induces expression of Tac antigen on human acute T lymphocytic leukemic cells. Volume 133 of Issue 2. 1984. PMID: 6330200


  351. Lipkowitz S, Greene WC, Rubin AL, Novogrodsky A, Stenzel KH. Expression of receptors for interleukin 2: Role in the commitment of T lymphocytes to proliferate. Volume 132 of Issue 1. 1984. PMID: 6418801


  352. Leonard WJ, Depper JM, Waldmann TA, Greene WC. In: Greaves M (Ed.), Receptors and Recognition 1984. PMID:


  353. Depper JM, Leonard WJ, Waldmann TA, Greene WC. In: Pick E (Ed.), Lymphokines 1984. PMID:


  355. Waldmann TA, Leonard WJ, Depper JM, Krönke M, Goldman CK, Oh T, Greene WC. Interleukin-2 receptor expression in retrovirus associated adult T-cell leukemia. Volume 15. 1984. PMID: 6100644


  356. Waldmann TA, Goldman CK, Leonard WJ, Depper JM, Robb RJ, Korsmeyer SJ, Greene WC. Interleukin-2 receptors on activated malignant and normal B-cells. Volume 113. 1984. PMID: 6236954


  357. Littman BH, Muchmore AV, Steinberg AD, Greene WC. Monoclonal lupus autoantibody secretion by human-human hybridomas. Selection of hybrids by conventional and novel techniques. Volume 72 of Issue 6. 1983. PMID: 6605979


  358. Leonard WJ, Depper JM, Robb RJ, Waldmann TA, Greene WC. Characterization of the human receptor for T-cell growth factor. Volume 80 of Issue 22. 1983. PMID: 6417659


  359. Lando Z, Sarin P, Megson M, Greene WC, Waldman TA, Gallo RC, Broder S. Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor. Volume 305 of Issue 5936. 1983. PMID: 6195529


  360. Robb RJ, Greene WC. Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen. Volume 158 of Issue 4. 1983. PMID: 6413637


  361. Depper JM, Leonard WJ, Robb RJ, Waldmann TA, Greene WC. Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation. Volume 131 of Issue 2. 1983. PMID: 6408186


  362. Korsmeyer SJ, Greene WC, Cossman J, Hsu SM, Jensen JP, Neckers LM, Marshall SL, Bakhshi A, Depper JM, Leonard WJ, Jaffe ES, Waldmann TA. Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia. Volume 80 of Issue 14. 1983. PMID: 6192435


  363. Koretzky GA, Daniele RP, Greene WC, Nowell PC. Evidence for an interleukin-independent pathway for human lymphocyte activation. Volume 80 of Issue 11. 1983. PMID: 6407014


  364. Cossman J, Neckers LM, Leonard WJ, Greene WC. Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen. Volume 157 of Issue 3. 1983. PMID: 6220104


  365. Greene WC, Depper JM, Leonard WJ, Fleisher TA, Waldmann TA. Construction of human suppressor T cell hybridomas. Volume 2 of Issue 2. 1983. PMID: 6236341


  366. Greene WC, Cossman J, Leonard WJ, Bakshi A, Waldmann TA, Korsmeyer SJ. In: Golde DW, Marks PA (Eds.), Normal and Neoplastic Hematopoiesis, UCLA Symposia on Molecular and Cellular Biology 1983. PMID:


  367. Blaese RM, Tosato G, Greene WC, Fleisher TA, Muchmore AV. The role of cell surface lectin--carbohydrate interactions in cellular recognition, cooperation, and regulation. Volume 5 of Issue 2. 1983. PMID: 6193722


  368. Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC. A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor. Volume 300 of Issue 5889. 1982. PMID: 6815536


  369. Greene WC, Fleisher TA, Nelson DL, Waldmann TA. Production of human suppressor T cell hybridomas. Volume 129 of Issue 5. 1982. PMID: 6214585


  371. Fleisher TA, Attallah AM, Tosato G, Blaese RM, Greene WC. Interferon-mediated inhibition of human polyclonal immunoglobulin synthesis. Volume 129 of Issue 3. 1982. PMID: 6179992


  372. Depper JM, Leonard WJ, Smith KA, Waldmann TA, Greene WC. In: Oppenheim JJ, Cohen S (Eds.), Interleukins, lymphokines, and cytokines 1982. PMID:


  374. Fleisher TA, Greene WC, Uchiyama T, Goldman CK, Nelson DL, Blaese RM, Waldmann TA. Characterization of a soluble suppressor of human B cell immunoglobulin biosynthesis produced by a continuous human suppressor T cell line. Volume 154 of Issue 1. 1981. PMID: 6454754


  378. Greene WC, Waldmann TA. Inhibition of human lymphocyte proliferation by the nonmitogenic lectin wheat germ agglutinin. Volume 124 of Issue 6. 1980. PMID: 6966300


  379. Parker CW, Greene WC. In: Cramer H, Schultz J (Eds.), Mechanism of Action 1977. PMID:


  380. Parker CW, Greene WC, MacDonald HH. Cytochalasin binding in lymphocytes and polymorphonuclear leukocytes. Volume 103 of Issue 1. 1976. PMID: 991953


  381. Greene WC, Parker CM, Parker CW. Cytochalasin sensitive structures and lymphocyte activation. Volume 103 of Issue 1. 1976. PMID: 186286


  382. Greene WC, Parker CM, Parker CW. Colchicine-sensitive structures and lymphocyte activation. Volume 117 of Issue 3. 1976. PMID: 956646


  384. Greene WC, Parker CM, Parker CW. Calcium and lymphocyte activation. Volume 25 of Issue 1. 1976. PMID: 183895


  385. Atkinson JP, Greene WC, McNearney TA, Parker CW. Studies on the stimulation of cAMP metabolism in human lymphocytes by latex polymers. Volume 99 of Issue 2. 1976. PMID: 178514


  389. Sullivan TJ, Greene WC, Parker CW. Concanavalin A-induced histamine release from normal rat mast cells. Volume 115 of Issue 1. 1975. PMID: 50352


  390. Peterson DT, Greene WC, Reaven GM. Effect of experimental diabetes mellitus on kidney ribosomal protein synthesis. Volume 20 of Issue 10. 1971. PMID: 5110696