Frederick Hecht, MD

Professor

I am trained in Internal Medicine, with additional training in clinical research methods, biostatistics, and behavioral medicine. My research focus for many years was on HIV. I developed one of the largest cohorts in the world of persons followed from primary HIV (within 6 months of infection), the Options Project, in which we have examined clinical, behavioral, cardiovascular, and immunologic research questions. In 2002, I became Director of Research at the UCSF Osher Center for Integrative Medicine. My research is driven by the belief that modern medicine has made impressive advances in treating a range of health conditions, but that further advances for many of the most important health problems of our era, including obesity, diabetes, heart disease, and mental health issues require improved development and implementation of lifestyle and other non-pharmacologic approaches. An important goal of my research program is to rigorously test whether we can improve interventions for chronic health problems such as HIV, diabetes, obesity, and stress, by incorporating mindfulness and/or yoga-based components. A current example is an NIH-funded study to test whether including training in mindful eating practices decreases eating in response to food cravings and enhances adherence to a nutritional plan in type 2 diabetes. I bring a focus on clinical research methodology to the projects I am involved with. I am particularly interested in the use of innovative research methodology to strengthen the rigor of research on nonpharmacolgic health interventions, including factorial trials and Sequential Multiple Assignment Randomized Trials (SMARTs), and assessment of teacher factors in mindfulness programs to improve intervention fidelity .

In my role as Director of the UCSF Osher Center Research Program, I have played a key leadership role in building it into an internationally recognized integrative medicine research center that is distinguished by the application of innovative and rigorous research designs to studying mindfulness-based interventions, yoga, acupuncture, interoceptive awareness, and behavioral interventions. I have served in a variety of leadership roles in HIV medicine and integrative health, including as board chair of the Academic Consortium for Integrative Medicine and Health, which gives me a broad view of the field. I have a strong commitment to mentoring. I have led UCSF’s highly successful Training Research in Integrative Medicine (TRIM) fellowship program since 2006, and have served as a primary or main co-mentor for 12 NIH K awardees. I have served as PI or co-PI/project director for 31 grants, 19 of them from NIH, including leading three Program Project grants.
Education
2019 - Diversity, Equity, and Inclusion Champion Training, University of California
Post-doctoral fellowship, 1993 - Clinical epidemiology -general internal medicine, University of California, San Francisco
1989 - Internal Medicine residency, Einstein-Montifiore Residency Program in Social Medicine
MD, 1986 - Medicine, SUNY Brooklyn
Websites
Publications

  1. Magombedze G, Vendrame E, SenGupta D, Geleziunas R, Little S, Smith D, Walker B, Routy JP, Hecht FM, Chun TW, Sneller M, Li JZ, Deeks SG, Peluso MJ. Early Viral Dynamics Predict HIV Post-Treatment Control After Analytic Treatment Interruption. 2024. PMID: 39513745


  2. Mehling WE, Strigo IA, Goldman V, Hartogensis W, Adler SR, Lotz J, Hecht FM. Mind your pain: A single-arm feasibility study to assess a smartphone-based interoceptive attention training for patients with chronic low back pain. 2024. PMID: 39446767


  4. Barbehenn A, Shi L, Shao J, Hoh R, Hartig HM, Pae V, Sarvadhavabhatla S, Donaire S, Sheikhzadeh C, Milush J, Laird GM, Mathias M, Ritter K, Peluso M, Martin J, Hecht F, Pilcher C, Cohen SE, Buchbinder S, Havlir D, Gandhi M, Henrich TJ, Hatano H, Wang J, Deeks SG, Lee SA. Rapid Biphasic Decay of Intact and Defective HIV DNA Reservoir During Acute Treated HIV Disease. 2024. PMID: 38585951


  5. Viswanath VK, Hartogenesis W, Dilchert S, Pandya L, Hecht FM, Mason AE, Wang EJ, Smarr BL. Five million nights: temporal dynamics in human sleep phenotypes. 2024. PMID: 38902390


  6. Ryan JM, Navaneethan S, Damaso N, Dilchert S, Hartogensis W, Natale JL, Hecht FM, Mason AE, Smarr BL. Information theory reveals physiological manifestations of COVID-19 that correlate with symptom density of illness. 2024. PMID: 38948084


  7. Dutcher EG, Epel ES, Mason AE, Hecht FM, Robinson JE, Drury SS, Prather AA. COVID-19 Vaccine Side Effects and Long-Term Neutralizing Antibody Response : A Prospective Cohort Study. 2024. PMID: 38857503


  8. Felder JN, Mirchandaney R, Manber R, Cuneo J, Krystal A, Solomon N, Janette S, Zhang L, Moran P, Mashash M, Epel E, Hecht FM. Feasibility and Acceptability of Mindfulness-based Stress Reduction and Prenatal Sleep Classes for Poor Prenatal Sleep Quality: Pilot Randomized Controlled Trial. 2024. PMID: 38850019


  9. Mason AE, Chowdhary A, Hartogensis W, Siwik CJ, Lupesko-Persky O, Pandya LS, Roberts S, Anglo C, Moran PJ, Nelson JC, Lowry CA, Patrick RP, Raison CL, Hecht FM. Feasibility and acceptability of an integrated mind-body intervention for depression: whole-body hyperthermia (WBH) and cognitive behavioral therapy (CBT). 2024. PMID: 38743265


  10. Mason AE, Kasl P, Soltani S, Green A, Hartogensis W, Dilchert S, Chowdhary A, Pandya LS, Siwik CJ, Foster SL, Nyer M, Lowry CA, Raison CL, Hecht FM, Smarr BL. Author Correction: Elevated body temperature is associated with depressive symptoms: results from the TemPredict Study. 2024. PMID: 38684772


  11. Kasl P, Keeler Bruce L, Hartogensis W, Dasgupta S, Pandya LS, Dilchert S, Hecht FM, Gupta A, Altintas I, Mason AE, Smarr BL. Utilizing Wearable Device Data for Syndromic Surveillance: A Fever Detection Approach. 2024. PMID: 38544080


  12. Volek JS, Yancy WS, Gower BA, Phinney SD, Slavin J, Koutnik AP, Hurn M, Spinner J, Cucuzzella M, Hecht FM. Expert consensus on nutrition and lower-carbohydrate diets: An evidence- and equity-based approach to dietary guidance. 2024. PMID: 38487629


  13. Hecht FM. Sedentary Behavior and Dementia. 2024. PMID: 38319336


  14. Mason AE, Kasl P, Soltani S, Green A, Hartogensis W, Dilchert S, Chowdhary A, Pandya LS, Siwik CJ, Foster SL, Nyer M, Lowry CA, Raison CL, Hecht FM, Smarr BL. Elevated body temperature is associated with depressive symptoms: results from the TemPredict Study. 2024. PMID: 38316806


  15. Dwivedi AK, Gornalusse GG, Siegel DA, Barbehenn A, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Reppetti J, Vo PM, Levy CN, Roychoudhury P, Jerome KR, Hladik F, Henrich TJ, Deeks SG, Lee SA. A cohort-based study of host gene expression: tumor suppressor and innate immune/inflammatory pathways associated with the HIV reservoir size. 2023. PMID: 38019897


  16. Bruce LK, Kasl P, Soltani S, Viswanath VK, Hartogensis W, Dilchert S, Hecht FM, Chowdhary A, Anglo C, Pandya L, Dasgupta S, Altintas I, Gupta A, Mason AE, Smarr BL. Correction: Variability of temperature measurements recorded by a wearable device by biological sex. 2023. PMID: 37957715


  17. Dutcher EG, Epel ES, Mason AE, Hecht FM, Robinson JE, Drury SS, Prather AA. The more symptoms the better? Covid-19 vaccine side effects and long-term neutralizing antibody response. 2023. PMID: 37808819


  18. Bruce LK, Kasl P, Soltani S, Viswanath VK, Hartogensis W, Dilchert S, Hecht FM, Chowdhary A, Anglo C, Pandya L, Dasgupta S, Altintas I, Gupta A, Mason AE, Smarr BL. Variability of temperature measurements recorded by a wearable device by biological sex. 2023. PMID: 37915069


  19. Reeves DB, Bacchus-Souffan C, Fitch M, Abdel-Mohsen M, Hoh R, Ahn H, Stone M, Hecht F, Martin J, Deeks SG, Hellerstein MK, McCune JM, Schiffer JT, Hunt PW. Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence. 2023. PMID: 37783718


  20. Saslow LR, Eslamian A, Moran P, Hartogensis W, Mason AE, Kim S, Bauer DC, Griauzde DH, Goldman V, Liu V, Stephens P, Raymond K, Yeung G, Leung C, Hecht FM. Protocol for a randomized controlled trial comparing a very low-carbohydrate diet or moderate-carbohydrate plate-method diet for type 2 diabetes: the LEGEND (Lifestyle Education about Nutrition for Diabetes) trial. 2023. PMID: 37475033


  21. Floyd E, Adler SR, Crane RS, Brewer J, Moran P, Richler R, Hartogensis W, Kuyken W, Hecht FM. The Reliability of Rating via Audio-Recording Using the Mindfulness-Based Interventions: Teaching Assessment Criteria. 2023. PMID: 37216036


  22. Saslow LR, Missel AL, O'Brien A, Kim S, Hecht FM, Moskowitz JT, Bayandorian H, Pietrucha M, Raymond K, Richards B, Liestenfeltz B, Mason AE, Daubenmier J, Aikens JE. Psychological Support Strategies for Adults With Type 2 Diabetes in a Very Low-Carbohydrate Web-Based Program: Randomized Controlled Trial. 2023. PMID: 37166961


  23. Prather AA, Dutcher EG, Robinson J, Lin J, Blackburn E, Hecht FM, Mason AE, Fromer E, Merino B, Frazier R, O'Bryan J, Drury S, Epel ES. Predictors of long-term neutralizing antibody titers following COVID-19 vaccination by three vaccine types: the BOOST study. 2023. PMID: 37160978


  24. Siwik CJ, Adler SR, Moran PJ, Kuyken W, Segal Z, Felder J, Eisendrath S, Hecht FM. Preventing Depression Relapse: A Qualitative Study on the Need for Additional Structured Support Following Mindfulness-Based Cognitive Therapy. 2023. PMID: 37077178


  25. Fisher K, Schlub TE, Boyer Z, Rasmussen TA, Rhodes A, Hoh R, Hecht FM, Deeks SG, Lewin SR, Palmer S. Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4. 2023. PMID: 36776833


  26. Dwivedi AK, Siegel DA, Thanh C, Hoh R, Hobbs KS, Pan T, Gibson EA, Martin J, Hecht F, Pilcher C, Milush J, Busch MP, Stone M, Huang ML, Levy CN, Roychoudhury P, Hladik F, Jerome KR, Henrich TJ, Deeks SG, Lee SA. Differences in expression of tumor suppressor, innate immune, inflammasome, and potassium/gap junction channel host genes significantly predict viral reservoir size during treated HIV infection. 2023. PMID: 36712077


  27. Wedrychowski A, Martin HA, Li Y, Telwatte S, Kadiyala GN, Melberg M, Etemad B, Connick E, Jacobson JM, Margolis DM, Skiest D, Volberding P, Hecht F, Deeks S, Wong JK, Li JZ, Yukl SA. Transcriptomic Signatures of Human Immunodeficiency Virus Post-Treatment Control. 2022. PMID: 36541802


  28. Siegel DA, Thanh C, Wan E, Hoh R, Hobbs K, Pan T, Gibson EA, Kroetz DL, Martin J, Hecht F, Pilcher C, Martin M, Carrington M, Pillai S, Busch MP, Stone M, Levy CN, Huang ML, Roychoudhury P, Hladik F, Jerome KR, Kiem HP, Henrich TJ, Deeks SG, Lee SA. Host variation in type I interferon signaling genes (MX1), C-C chemokine receptor type 5 gene, and major histocompatibility complex class I alleles in treated HIV+ noncontrollers predict viral reservoir size. 2022. PMID: 36695358


  29. Klein A, Puldon K, Dilchert S, Hartogensis W, Chowdhary A, Anglo C, Pandya LS, Hecht FM, Mason AE, Smarr BL. Methods for detecting probable COVID-19 cases from large-scale survey data also reveal probable sex differences in symptom profiles. 2022. PMID: 36438983


  31. Stern J, Solomon A, Dantanarayana A, Pascoe R, Reynaldi A, Davenport MP, Milush J, Deeks SG, Hartogensis W, Hecht FM, Cockerham L, Roche M, Lewin SR. Cell-associated HIV RNA has a Circadian Cycle in Males Living with HIV on Antiretroviral Therapy. 2021. PMID: 34655216


  32. Horsburgh BA, Hiener B, Fisher K, Lee E, Morgan H, Eden JS, von Stockenstrom S, Odevall L, Milush JM, Hoh R, Fromentin R, Chomont N, Hecht FM, Schlub TE, Deeks SG, Palmer S. Cellular activation, differentiation and proliferation influence the dynamics of genetically-intact proviruses over time. 2021. PMID: 34037766


  33. Felder JN, Mirchandaney R, Harrison J, Manber R, Cuneo J, Krystal A, Epel E, Hecht F. Examining Experiences of Poor Sleep During Pregnancy: A Qualitative Study to Inform the Development of a Prenatal Sleep Intervention. 2022. PMID: 35360508


  34. Mason AE, Hecht FM, Davis SK, Natale JL, Hartogensis W, Damaso N, Claypool KT, Dilchert S, Dasgupta S, Purawat S, Viswanath VK, Klein A, Chowdhary A, Fisher SM, Anglo C, Puldon KY, Veasna D, Prather JG, Pandya LS, Fox LM, Busch M, Giordano C, Mercado BK, Song J, Jaimes R, Baum BS, Telfer BA, Philipson CW, Collins PP, Rao AA, Wang EJ, Bandi RH, Choe BJ, Epel ES, Epstein SK, Krasnoff JB, Lee MB, Lee SW, Lopez GM, Mehta A, Melville LD, Moon TS, Mujica-Parodi LR, Noel KM, Orosco MA, Rideout JM, Robishaw JD, Rodriguez RM, Shah KH, Siegal JH, Gupta A, Altintas I, Smarr BL. Author Correction: Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study. 2022. PMID: 35296773


  35. Smarr BL, Aschbacher K, Fisher SM, Chowdhary A, Dilchert S, Puldon K, Rao A, Hecht FM, Mason AE. Author Correction: Feasibility of continuous fever monitoring using wearable devices. 2022. PMID: 35292699


  36. Mason AE, Hecht FM, Davis SK, Natale JL, Hartogensis W, Damaso N, Claypool KT, Dilchert S, Dasgupta S, Purawat S, Viswanath VK, Klein A, Chowdhary A, Fisher SM, Anglo C, Puldon KY, Veasna D, Prather JG, Pandya LS, Fox LM, Busch M, Giordano C, Mercado BK, Song J, Jaimes R, Baum BS, Telfer BA, Philipson CW, Collins PP, Rao AA, Wang EJ, Bandi RH, Choe BJ, Epel ES, Epstein SK, Krasnoff JB, Lee MB, Lee SW, Lopez GM, Mehta A, Melville LD, Moon TS, Mujica-Parodi LR, Noel KM, Orosco MA, Rideout JM, Robishaw JD, Rodriguez RM, Shah KH, Siegal JH, Gupta A, Altintas I, Smarr BL. Detection of COVID-19 using multimodal data from a wearable device: results from the first TemPredict Study. 2022. PMID: 35236896


  37. Mason AE, Kasl P, Hartogensis W, Natale JL, Dilchert S, Dasgupta S, Purawat S, Chowdhary A, Anglo C, Veasna D, Pandya LS, Fox LM, Puldon KY, Prather JG, Gupta A, Altintas I, Smarr BL, Hecht FM. Metrics from Wearable Devices as Candidate Predictors of Antibody Response Following Vaccination against COVID-19: Data from the Second TemPredict Study. 2022. PMID: 35214723


  38. Van Blarigan EL, Dhruva A, Atreya CE, Kenfield SA, Chan JM, Milloy A, Kim I, Steiding P, Laffan A, Zhang L, Piawah S, Fukuoka Y, Miaskowski C, Hecht FM, Kim MO, Venook AP, Van Loon K. Feasibility and Acceptability of a Physical Activity Tracker and Text Messages to Promote Physical Activity During Chemotherapy for Colorectal Cancer: Pilot Randomized Controlled Trial (Smart Pace II). 2022. PMID: 35014958


  39. Dragomanovich HM, Dhruva A, Ekman E, Schoenbeck KL, Kubo A, Van Blarigan EL, Borno HT, Esquivel M, Chee B, Campanella M, Philip EJ, Rettger JP, Rosenthal B, Van Loon K, Venook AP, Boscardin C, Moran P, Hecht FM, Atreya CE. Being Present 2.0: Online Mindfulness-Based Program for Metastatic Gastrointestinal Cancer Patients and Caregivers. 2021. PMID: 35174001


  40. Fajnzylber J, Sharaf R, Hutchinson JN, Aga E, Bosch RJ, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest DJ, Margolis D, Sneller MC, Little SJ, Gulick RM, Mellors JW, Gandhi RT, Schooley RT, Henry K, Tebas P, Deeks S, Chun TW, Collier AC, Hecht FM, Li JZ, CHAMP study team. Frequency of Post Treatment Control Varies by ART Restart and Viral Load Criteria. 2021. PMID: 34127579


  41. Jake-Schoffman DE, Brown SD, Baiocchi M, Bibeau JL, Daubenmier J, Ferrara A, Galarce MN, Hartogensis W, Hecht FM, Hedderson MM, Moran PJ, Pagoto SL, Tsai AL, Waring ME, Kiernan M. Methods-Motivational Interviewing Approach for Enhanced Retention and Attendance. 2021. PMID: 34544560


  42. Volek JS, Phinney SD, Krauss RM, Johnson RJ, Saslow LR, Gower B, Yancy WS, King JC, Hecht FM, Teicholz N, Bistrian BR, Hamdy O. Alternative Dietary Patterns for Americans: Low-Carbohydrate Diets. 2021. PMID: 34684300


  43. Morcilla V, Bacchus-Souffan C, Fisher K, Horsburgh BA, Hiener B, Wang XQ, Schlub TE, Fitch M, Hoh R, Hecht FM, Martin JN, Deeks SG, Hellerstein MK, McCune JM, Hunt PW, Palmer S. HIV-1 Genomes Are Enriched in Memory CD4+ T-Cells with Short Half-Lives. 2021. PMID: 34544282


  44. Daubenmier J, Chao MT, Hartogensis W, Liu R, Moran PJ, Acree MC, Kristeller J, Epel ES, Hecht FM. Exploratory Analysis of Racial/Ethnic and Educational Differences in a Randomized Controlled Trial of a Mindfulness-Based Weight Loss Intervention. 2021. PMID: 33214537


  45. Schnittman SR, Deitchman AN, Beck-Engeser G, Ahn H, York VA, Hartig H, Hecht FM, Martin JN, Deeks SG, Aweeka FT, Hunt PW. Some But Not All Biomarkers of Immune Activation Remain Abnormal Despite Very Early Treatment of HIV. 2020. PMID: 32915986


  46. Wang P, Hecht F, Ossato G, Tille S, Fraser SE, Junge JA. Complex wavelet filter improves FLIM phasors for photon starved imaging experiments. 2021. PMID: 34221672


  47. Lebares CC, Coaston TN, Delucchi KL, Guvva EV, Shen WT, Staffaroni AM, Kramer JH, Epel ES, Hecht FM, Ascher NL, Harris HW, Cole SW. Enhanced Stress Resilience Training in Surgeons: Iterative Adaptation and Biopsychosocial Effects in 2 Small Randomized Trials. 2021. PMID: 32773637


  48. Rutishauser RL, Deguit CDT, Hiatt J, Blaeschke F, Roth TL, Wang L, Raymond KA, Starke CE, Mudd JC, Chen W, Smullin CP, Matus-Nicodemos R, Hoh R, Krone MR, Hecht FM, Pilcher CD, Martin JN, Koup RA, Douek DC, Brenchley JM, Sékaly RP, Pillai SK, Marson A, Deeks SG, McCune JM, Hunt PW. TCF-1 regulates HIV-specific CD8+ T cell expansion capacity. 2020. PMID: 33351785


  49. Bacchus-Souffan C, Fitch M, Symons J, Abdel-Mohsen M, Reeves DB, Hoh R, Stone M, Hiatt J, Kim P, Chopra A, Ahn H, York VA, Cameron DL, Hecht FM, Martin JN, Yukl SA, Mallal S, Cameron PU, Deeks SG, Schiffer JT, Lewin SR, Hellerstein MK, McCune JM, Hunt PW. Relationship between CD4 T cell turnover, cellular differentiation and HIV persistence during ART. 2021. PMID: 33465157


  50. Weng HY, Ikeda MP, Lewis-Peacock JA, Chao MT, Fullwiley D, Goldman V, Skinner S, Duncan LG, Gazzaley A, Hecht FM. Corrigendum: Toward a Compassionate Intersectional Neuroscience: Increasing Diversity and Equity in Contemplative Neuroscience. 2021. PMID: 33488490


  51. Smarr BL, Aschbacher K, Fisher SM, Chowdhary A, Dilchert S, Puldon K, Rao A, Hecht FM, Mason AE. Feasibility of continuous fever monitoring using wearable devices. 2020. PMID: 33318528


  52. Dhruva A, Wu C, Miaskowski C, Hartogensis W, Rugo HS, Adler SR, Kaptchuk TJ, Kelkar R, Agarawal S, Vadodaria A, Garris E, Hecht FM. A 4-Month Whole-Systems Ayurvedic Medicine Nutrition and Lifestyle Intervention Is Feasible and Acceptable for Breast Cancer Survivors: Results of a Single-Arm Pilot Clinical Trial. 2020. PMID: 33312762


  53. Weng HY, Ikeda MP, Lewis-Peacock JA, Chao MT, Fullwiley D, Goldman V, Skinner S, Duncan LG, Gazzaley A, Hecht FM. Toward a Compassionate Intersectional Neuroscience: Increasing Diversity and Equity in Contemplative Neuroscience. 2020. PMID: 33329215


  54. S Crane R, Hecht FM, Brewer J, Griffith GM, Hartogensis W, Koerbel L, Moran P, Sansom S, Yiangou A, Kuyken W. Can We Agree What Skilled Mindfulness-Based Teaching Looks Like? Lessons From Studying the MBI:TAC. 2020. PMID: 33110709


  56. Saslow LR, Moskowitz JT, Mason AE, Daubenmier J, Liestenfeltz B, Missel AL, Bayandorian H, Aikens JE, Kim S, Hecht FM. Intervention Enhancement Strategies Among Adults With Type 2 Diabetes in a Very Low-Carbohydrate Web-Based Program: Evaluating the Impact With a Randomized Trial. 2020. PMID: 32902391


  57. Weng HY, Lewis-Peacock JA, Hecht FM, Uncapher MR, Ziegler DA, Farb NAS, Goldman V, Skinner S, Duncan LG, Chao MT, Gazzaley A. Focus on the Breath: Brain Decoding Reveals Internal States of Attention During Meditation. 2020. PMID: 33005138


  58. Scharf L, Tauriainen J, Buggert M, Hartogensis W, Nolan DJ, Deeks SG, Salemi M, Hecht FM, Karlsson AC. Delayed Expression of PD-1 and TIGIT on HIV-Specific CD8 T Cells in Untreated HLA-B*57:01 Individuals Followed from Early Infection. 2020. PMID: 32350076


  59. Antar AA, Jenike KM, Jang S, Rigau DN, Reeves DB, Hoh R, Krone MR, Keruly JC, Moore RD, Schiffer JT, Nonyane BA, Hecht FM, Deeks SG, Siliciano JD, Ho YC, Siliciano RF. Longitudinal study reveals HIV-1-infected CD4+ T cell dynamics during long-term antiretroviral therapy. 2020. PMID: 32191639


  61. Li Y, Altan E, Pilcher C, Hartogensis W, Hecht FM, Deng X, Delwart E. Semen virome of men with HIV on or off antiretroviral treatment. 2020. PMID: 32271249


  62. Horsburgh BA, Lee E, Hiener B, Eden JS, Schlub TE, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek DC, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. High levels of genetically intact HIV in HLA-DR+ memory T cells indicates their value for reservoir studies. 2020. PMID: 31913161


  63. Anderson JL, Khoury G, Fromentin R, Solomon A, Chomont N, Sinclair E, Milush JM, Hartogensis W, Bacchetti P, Roche M, Tumpach C, Gartner M, Pitman MC, Epling CL, Hoh R, Hecht FM, Somsouk M, Cameron PU, Deeks SG, Lewin SR. Human Immunodeficiency Virus (HIV)-Infected CCR6+ Rectal CD4+ T Cells and HIV Persistence On Antiretroviral Therapy. 2020. PMID: 31796951


  64. Lee E, von Stockenstrom S, Morcilla V, Odevall L, Hiener B, Shao W, Hartogensis W, Bacchetti P, Milush J, Liegler T, Sinclair E, Hatano H, Hoh R, Somsouk M, Hunt P, Boritz E, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. The impact of antiretroviral therapy duration on the HIV-1 infection of T-cells within anatomic sites. 2019. PMID: 31723024


  65. Mason AE, Saslow L, Moran PJ, Kim S, Wali PK, Abousleiman H, Hartman A, Richler R, Schleicher S, Hartogensis W, Epel ES, Hecht F. Correction: Examining the Effects of Mindful Eating Training on Adherence to a Carbohydrate-Restricted Diet in Patients With Type 2 Diabetes (the DELISH Study): Protocol for a Randomized Controlled Trial. 2020. PMID: 31929107


  66. Mason AE, Saslow LR, Moran PJ, Kim S, Wali PK, Abousleiman H, Richler R, Schleicher S, Goldman VM, Hartman A, Leung C, Hartogensis W, Hecht FM. Correction to: Lipid findings from the Diabetes Education to Lower Insulin, Sugars, and Hunger (DELISH) Study. 2019. PMID: 31892933


  67. Hecht FM. Ketogenic Diets for Diabetes and Obesity. 2019. PMID: 31790525


  68. Radin RM, Epel ES, Daubenmier J, Moran P, Schleicher S, Kristeller J, Hecht FM, Mason AE. Do stress eating or compulsive eating influence metabolic health in a mindfulness-based weight loss intervention? 2019. PMID: 31724424


  69. Chao MT, Schillinger D, Nguyen U, Santana T, Liu R, Gregorich S, Hecht FM. A Randomized Clinical Trial of Group Acupuncture for Painful Diabetic Neuropathy Among Diverse Safety Net Patients. 2019. PMID: 31127837


  70. Epel E, Laraia B, Coleman-Phox K, Leung C, Vieten C, Mellin L, Kristeller JL, Thomas M, Stotland N, Bush N, Lustig RH, Dallman M, Hecht FM, Adler N. Effects of a Mindfulness-Based Intervention on Distress, Weight Gain, and Glucose Control for Pregnant Low-Income Women: A Quasi-Experimental Trial Using the ORBIT Model. 2019. PMID: 30993601


  71. Hu H, Shear D, Thakkar R, Thompson-Lastad A, Pinderhughes H, Hecht FM, Lown EA. Acupressure and Therapeutic Touch in Childhood Cancer to Promote Subjective and Intersubjective Experiences of Well-being During Curative Treatment. 2019. PMID: 31632842


  72. Lee E, Bacchetti P, Milush J, Shao W, Boritz E, Douek D, Fromentin R, Liegler T, Hoh R, Deeks SG, Hecht FM, Chomont N, Palmer S. Memory CD4 + T-Cells Expressing HLA-DR Contribute to HIV Persistence During Prolonged Antiretroviral Therapy. 2019. PMID: 31611857


  73. Daubenmier J, Epel ES, Moran PJ, Thompson J, Mason AE, Acree M, Goldman V, Kristeller J, Hecht FM, Mendes WB. A Randomized Controlled Trial of a Mindfulness-Based Weight Loss Intervention on Cardiovascular Reactivity to Social-Evaluative Threat Among Adults with Obesity. 2019. PMID: 32266044


  74. Mason AE, Saslow LR, Moran PJ, Kim S, Abousleiman H, Richler R, Schleicher S, Goldman VM, Hartman A, Leung C, Hartogensis W, Hecht FM. Lipid findings from the Diabetes Education to Lower Insulin, Sugars, and Hunger (DELISH) Study. 2019. PMID: 31467583


  75. Lown EA, Banerjee A, Vittinghoff E, Dvorak CC, Hartogensis W, Melton A, Mangurian C, Hu H, Shear D, Adcock R, Morgan M, Golden C, Hecht FM. Acupressure to Reduce Treatment-Related Symptoms for Children With Cancer and Recipients of Hematopoietic Stem Cell Transplant: Protocol for a Randomized Controlled Trial. 2019. PMID: 31453017


  77. Mason AE, Saslow L, Moran PJ, Kim S, Wali PK, Abousleiman H, Hartman A, Richler R, Schleicher S, Hartogensis W, Epel ES, Hecht F. Examining the Effects of Mindful Eating Training on Adherence to a Carbohydrate-Restricted Diet in Patients With Type 2 Diabetes (the DELISH Study): Protocol for a Randomized Controlled Trial. 2019. PMID: 30545813


  78. Fromentin R, DaFonseca S, Costiniuk CT, El-Far M, Procopio FA, Hecht FM, Hoh R, Deeks SG, Hazuda DJ, Lewin SR, Routy JP, Sékaly RP, Chomont N. PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals. 2019. PMID: 30778080


  79. Namazi G, Fajnzylber JM, Aga E, Bosch RJ, Acosta EP, Sharaf R, Hartogensis W, Jacobson JM, Connick E, Volberding P, Skiest D, Margolis D, Sneller MC, Little SJ, Gianella S, Smith DM, Kuritzkes DR, Gulick RM, Mellors JW, Mehraj V, Gandhi RT, Mitsuyasu R, Schooley RT, Henry K, Tebas P, Deeks SG, Chun TW, Collier AC, Routy JP, Hecht FM, Walker BD, Li JZ. The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies. 2018. PMID: 30085241


  80. Chang CC, Naranbhai V, Stern J, Roche M, Dantanarayana A, Ke R, Tennakoon S, Solomon A, Hoh R, Hartogensis W, Hecht FM, Sikaris K, Price DJ, Elliott JH, Deeks SG, Churchill M, Cameron PU, Hengartner N, Perelson AS, Lewin SR. Variation in cell-associated unspliced HIV RNA on antiretroviral therapy is associated with the circadian regulator brain-and-muscle-ARNT-like-1. 2018. PMID: 30005017


  81. Lebares CC, Braun HJ, Guvva EV, Epel ES, Hecht FM. Burnout and gender in surgical training: A call to re-evaluate coping and dysfunction. 2018. PMID: 30197022


  82. Mason AE, Hecht FM, Daubenmier JJ, Sbarra DA, Lin J, Moran PJ, Schleicher SG, Acree M, Prather AA, Epel ES. Weight Loss Maintenance and Cellular Aging in the Supporting Health Through Nutrition and Exercise Study. 2018. PMID: 29901486


  83. Hecht FM, Moskowitz JT, Moran P, Epel ES, Bacchetti P, Acree M, Kemeny ME, Mendes WB, Duncan LG, Weng H, Levy JA, Deeks SG, Folkman S. A randomized, controlled trial of mindfulness-based stress reduction in HIV infection. 2018. PMID: 29842903


  84. Mascarenhas MN, Chan JM, Vittinghoff E, Van Blarigan EL, Hecht F. Increasing Physical Activity in Mothers Using Video Exercise Groups and Exercise Mobile Apps: Randomized Controlled Trial. 2018. PMID: 29776899


  86. Laraia BA, Adler NE, Coleman-Phox K, Vieten C, Mellin L, Kristeller JL, Thomas M, Stotland NE, Lustig RH, Dallman MF, Hecht FM, Bush NR, de Groat CL, Epel E. Novel Interventions to Reduce Stress and Overeating in Overweight Pregnant Women: A Feasibility Study. 2018. PMID: 29455384


  87. Batchelder AW, Carrico AW, Acree M, Hecht FM, Moskowitz JT. Positive and Negative Self-Conscious Emotion and Transmission Risk Following HIV Diagnosis. 2018. PMID: 29086116


  88. Crane RS, Hecht FM. Intervention Integrity in Mindfulness-Based Research. 2018. PMID: 30294386


  89. Kiniry BE, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. Differential Expression of CD8+ T Cell Cytotoxic Effector Molecules in Blood and Gastrointestinal Mucosa in HIV-1 Infection. 2018. PMID: 29352005


  90. Saslow LR, Daubenmier JJ, Moskowitz JT, Kim S, Murphy EJ, Phinney SD, Ploutz-Snyder R, Goldman V, Cox RM, Mason AE, Moran P, Hecht FM. Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes. 2017. PMID: 29269731


  91. Hiener B, Horsburgh BA, Eden JS, Barton K, Schlub TE, Lee E, von Stockenstrom S, Odevall L, Milush JM, Liegler T, Sinclair E, Hoh R, Boritz EA, Douek D, Fromentin R, Chomont N, Deeks SG, Hecht FM, Palmer S. Identification of Genetically Intact HIV-1 Proviruses in Specific CD4+ T Cells from Effectively Treated Participants. 2017. PMID: 29045846


  92. de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF, Michaud HA. Anti-HERV-K (HML-2) capsid antibody responses in HIV elite controllers. 2017. PMID: 28830571


  93. Gurfein BT, Hasdemir B, Milush JM, Touma C, Palme R, Nixon DF, Darcel N, Hecht FM, Bhargava A. Enriched environment and stress exposure influence splenic B lymphocyte composition. 2017. PMID: 28704473


  94. Keating SM, Pilcher CD, Jain V, Lebedeva M, Hampton D, Abdel-Mohsen M, Deng X, Murphy G, Welte A, Facente SN, Hecht F, Deeks SG, Pillai SK, Busch MP. HIV Antibody Level as a Marker of HIV Persistence and Low-Level Viral Replication. Volume 216 of Issue 1. 2017. PMID: 28498985


  95. Mason AE, Vainik U, Acree M, Tomiyama AJ, Dagher A, Epel ES, Hecht FM. Improving Assessment of the Spectrum of Reward-Related Eating: The RED-13. 2017. PMID: 28611698


  96. Rutishauser RL, Hartogensis W, Deguit CD, Krone M, Hoh R, Hecht FM, Pilcher CD, Bacchetti P, Deeks SG, Hunt PW, McCune JM. Early and Delayed Antiretroviral Therapy Results in Comparable Reductions in CD8+ T Cell Exhaustion Marker Expression. Volume 33 of Issue 7. 2017. PMID: 28335609


  97. Charlins P, Schmitt K, Remling-Mulder L, Hogan LE, Hanhauser E, Hobbs KS, Hecht F, Deeks SG, Henrich TJ, Akkina R. A humanized mouse-based HIV-1 viral outgrowth assay with higher sensitivity than in vitro qVOA in detecting latently infected cells from individuals on ART with undetectable viral loads. 2017. PMID: 28432928


  98. Khoury G, Fromentin R, Solomon A, Hartogensis W, Killian M, Hoh R, Somsouk M, Hunt PW, Girling V, Sinclair E, Bacchetti P, Anderson JL, Hecht FM, Deeks SG, Cameron PU, Chomont N, Lewin SR. Human Immunodeficiency Virus Persistence and T-Cell Activation in Blood, Rectal, and Lymph Node Tissue in Human Immunodeficiency Virus-Infected Individuals Receiving Suppressive Antiretroviral Therapy. Volume 215 of Issue 6. 2017. PMID: 28453847


  100. Palar K, Napoles T, Hufstedler LL, Seligman H, Hecht FM, Madsen K, Ryle M, Pitchford S, Frongillo EA, Weiser SD. Comprehensive and Medically Appropriate Food Support Is Associated with Improved HIV and Diabetes Health. Volume 94 of Issue 1. 2017. PMID: 28097614


  101. Henje Blom E, Tymofiyeva O, Chesney MA, Ho TC, Moran P, Connolly CG, Duncan LG, Baldini L, Weng HY, Acree M, Goldman V, Hecht FM, Yang TT. Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: "Training for Awareness Resilience and Action" (TARA)-A Pilot Study. 2017. PMID: 28138319


  102. Tauriainen J, Scharf L, Frederiksen J, Naji A, Ljunggren HG, Sönnerborg A, Lund O, Reyes-Terán G, Hecht FM, Deeks SG, Betts MR, Buggert M, Karlsson AC. Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals. 2017. PMID: 28084312


  103. Adler E, Dhruva A, Moran PJ, Daubenmier J, Acree M, Epel ES, Bacchetti P, Prather AA, Mason A, Hecht FM. Impact of a Mindfulness-Based Weight-Loss Intervention on Sleep Quality Among Adults with Obesity: Data from the SHINE Randomized Controlled Trial. 2016. PMID: 28029852


  104. Pinzone MR, Graf E, Lynch L, McLaughlin B, Hecht FM, Connors M, Migueles SA, Hwang WT, Nunnari G, O'Doherty U. Monitoring Integration over Time Supports a Role for Cytotoxic T Lymphocytes and Ongoing Replication as Determinants of Reservoir Size. 2016. PMID: 27630237


  105. Kiniry BE, Ganesh A, Critchfield JW, Hunt PW, Hecht FM, Somsouk M, Deeks SG, Shacklett BL. Predominance of weakly cytotoxic, T-betLowEomesNeg CD8+ T-cells in human gastrointestinal mucosa: implications for HIV infection. Volume 10 of Issue 4. 2016. PMID: 27827375


  106. Nititham J, Gupta R, Zeng X, Hartogensis W, Nixon DF, Deeks SG, Hecht FM, Liao W. Psoriasis risk SNPs and their association with HIV-1 control. 2016. PMID: 27810495


  107. Kassanjee R, Pilcher CD, Busch MP, Murphy G, Facente SN, Keating SM, Mckinney E, Marson K, Price MA, Martin JN, Little SJ, Hecht FM, Kallas EG, Welte A. Viral load criteria and threshold optimization to improve HIV incidence assay characteristics. 2016. PMID: 27454561


  108. Willberg CB, Garrison KE, Jones RB, Meiklejohn DA, Spotts G, Liegler TJ, Ostrowski MA, Karlsson AC, Hecht FM, Nixon DF. Correction: Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes. 2016. PMID: 27454121


  109. Fromentin R, Bakeman W, Lawani MB, Khoury G, Hartogensis W, DaFonseca S, Killian M, Epling L, Hoh R, Sinclair E, Hecht FM, Bacchetti P, Deeks SG, Lewin SR, Sékaly RP, Chomont N. CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART. 2016. PMID: 27415008


  110. Ramirez CM, Sinclair E, Epling L, Lee SA, Jain V, Hsue PY, Hatano H, Conn D, Hecht FM, Martin JN, McCune JM, Deeks SG, Hunt PW. Immunologic profiles distinguish aviremic HIV-infected adults. Volume 30 of Issue 10. 2016. PMID: 26854811


  111. Khoury G, Anderson JL, Fromentin R, Hartogenesis W, Smith MZ, Bacchetti P, Hecht FM, Chomont N, Cameron PU, Deeks SG, Lewin SR. Persistence of integrated HIV DNA in CXCR3 + CCR6 + memory CD4+ T cells in HIV-infected individuals on antiretroviral therapy. 2016. PMID: 26807971


  112. Chao MT, Chang A, Reddy S, Harrison JD, Acquah J, Toveg M, Santana T, Hecht FM. Adjunctive acupuncture for pain and symptom management in the inpatient setting: protocol for a pilot hybrid effectiveness-implementation study. 2016. PMID: 27181130


  113. Daubenmier J, Moran PJ, Kristeller J, Acree M, Bacchetti P, Kemeny ME, Dallman M, Lustig RH, Grunfeld C, Nixon DF, Milush JM, Goldman V, Laraia B, Laugero KD, Woodhouse L, Epel ES, Hecht FM. Effects of a mindfulness-based weight loss intervention in adults with obesity: A randomized clinical trial. 2016. PMID: 26955895


  114. Mason AE, Epel ES, Aschbacher K, Lustig RH, Acree M, Kristeller J, Cohn M, Dallman M, Moran PJ, Bacchetti P, Laraia B, Hecht FM, Daubenmier J. Reduced reward-driven eating accounts for the impact of a mindfulness-based diet and exercise intervention on weight loss: Data from the SHINE randomized controlled trial. 2016. PMID: 26867697


  115. Prather AA, Hecht FM, Epel ES. Factors related to telomere length. 2016. PMID: 26851133


  116. Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Maurer M, Korman AJ, Deeks SG, Sacha JB, Ndhlovu LC. TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection. 2016. PMID: 26741490


  117. Stuempfle KJ, Valentino T, Hew-Butler T, Hecht FM, Hoffman MD. Nausea is associated with endotoxemia during a 161-km ultramarathon. 2015. PMID: 26707127


  118. Mason AE, Epel ES, Kristeller J, Moran PJ, Dallman M, Lustig RH, Acree M, Bacchetti P, Laraia BA, Hecht FM, Daubenmier J. Effects of a mindfulness-based intervention on mindful eating, sweets consumption, and fasting glucose levels in obese adults: data from the SHINE randomized controlled trial. 2015. PMID: 26563148


  119. Pilcher CD, Bisol CA, Paganella MP, Vallabhaneni S, da Motta LR, Kato SK, Sperhacke RD, Kallas EG, Hecht FM, Diaz RS. Efficient Identification of HIV Serodiscordant Couples by Existing HIV Testing Programs in South Brazil. 2015. PMID: 26562436


  120. Vujkovic-Cvijin I, Swainson LA, Chu SN, Ortiz AM, Santee CA, Petriello A, Dunham RM, Fadrosh DW, Lin DL, Faruqi AA, Huang Y, Apetrei C, Pandrea I, Hecht FM, Pilcher CD, Klatt NR, Brenchley JM, Lynch SV, McCune JM. Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques. 2015. PMID: 26586432


  121. Whittle HJ, Palar K, Napoles T, Hufstedler LL, Ching I, Hecht FM, Frongillo EA, Weiser SD. Experiences with food insecurity and risky sex among low-income people living with HIV/AIDS in a resource-rich setting. Volume 18. 2015. PMID: 26546789


  122. Moskowitz JT, Duncan LG, Moran PJ, Acree M, Epel ES, Kemeny ME, Hecht FM, Folkman S. Dispositional Mindfulness in People with HIV: Associations with Psychological and Physical Health. 2015. PMID: 26240472


  124. McDermott K, Kumar D, Goldman V, Feng H, Mehling W, Moskowitz JT, Souza RB, Hecht FM. Training in ChiRunning to reduce blood pressure: a randomized controlled pilot study. 2015. PMID: 26471194


  125. Gornalusse GG, Mummidi S, Gaitan AA, Jimenez F, Ramsuran V, Picton A, Rogers K, Manoharan MS, Avadhanam N, Murthy KK, Martinez H, Molano Murillo A, Chykarenko ZA, Hutt R, Daskalakis D, Shostakovich-Koretskaya L, Abdool Karim S, Martin JN, Deeks SG, Hecht F, Sinclair E, Clark RA, Okulicz J, Valentine FT, Martinson N, Tiemessen CT, Ndung'u T, Hunt PW, He W, Ahuja SK. Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor. Volume 112 of Issue 34. 2015. PMID: 26307764


  126. Mason AE, Laraia B, Daubenmier J, Hecht FM, Lustig RH, Puterman E, Adler N, Dallman M, Kiernan M, Gearhardt AN, Epel ES. Putting the brakes on the "drive to eat": Pilot effects of naltrexone and reward-based eating on food cravings among obese women. 2015. PMID: 26164674


  127. Procopio FA, Fromentin R, Kulpa DA, Brehm JH, Bebin AG, Strain MC, Richman DD, O'Doherty U, Palmer S, Hecht FM, Hoh R, Barnard RJ, Miller MD, Hazuda DJ, Deeks SG, Sékaly RP, Chomont N. A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals. 2015. PMID: 26425694


  128. Eriksson EM, Liegler T, Keh CE, Karlsson AC, Holditch SJ, Pilcher CD, Loeb L, Nixon DF, Hecht FM. Newly Exerted T Cell Pressures on Mutated Epitopes following Transmission Help Maintain Consensus HIV-1 Sequences. 2015. PMID: 25919393


  129. Mason AE, Lustig RH, Brown RR, Acree M, Bacchetti P, Moran PJ, Dallman M, Laraia B, Adler N, Hecht FM, Daubenmier J, Epel ES. Acute responses to opioidergic blockade as a biomarker of hedonic eating among obese women enrolled in a mindfulness-based weight loss intervention trial. 2015. PMID: 25931433


  131. Mehling WE, Avins AL, Acree MC, Carey TS, Hecht FM. Can a back pain screening tool help classify patients with acute pain into risk levels for chronic pain? 2015. PMID: 25381748


  132. von Stockenstrom S, Odevall L, Lee E, Sinclair E, Bacchetti P, Killian M, Epling L, Shao W, Hoh R, Ho T, Faria NR, Lemey P, Albert J, Hunt P, Loeb L, Pilcher C, Poole L, Hatano H, Somsouk M, Douek D, Boritz E, Deeks SG, Hecht FM, Palmer S. Longitudinal Genetic Characterization Reveals That Cell Proliferation Maintains a Persistent HIV Type 1 DNA Pool During Effective HIV Therapy. Volume 212 of Issue 4. 2015. PMID: 25712966


  133. Abdel-Mohsen M, Wang C, Strain MC, Lada SM, Deng X, Cockerham LR, Pilcher CD, Hecht FM, Liegler T, Richman DD, Deeks SG, Pillai SK. Select host restriction factors are associated with HIV persistence during antiretroviral therapy. Volume 29 of Issue 4. 2015. PMID: 25602681


  134. Kumar D, McDermott K, Feng H, Goldman V, Luke A, Souza RB, Hecht FM. Effects of Form-Focused Training on Running Biomechanics: A Pilot Randomized Trial in Untrained Individuals. 2015. PMID: 25633634


  135. Gega A, Kozal MJ, Chiarella J, Lee E, Peterson J, Hecht FM, Liegler T, St John EP, Simen BB, Price RW, Spudich SS. Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection. 2015. PMID: 26855971


  136. Hollingsworth TD, Pilcher CD, Hecht FM, Deeks SG, Fraser C. High Transmissibility During Early HIV Infection Among Men Who Have Sex With Men-San Francisco, California. 2014. PMID: 25542958


  137. Prather AA, Gurfein B, Moran P, Daubenmier J, Acree M, Bacchetti P, Sinclair E, Lin J, Blackburn E, Hecht FM, Epel ES. Tired telomeres: Poor global sleep quality, perceived stress, and telomere length in immune cell subsets in obese men and women. 2014. PMID: 25535858


  138. Cockerham LR, Siliciano JD, Sinclair E, O'Doherty U, Palmer S, Yukl SA, Strain MC, Chomont N, Hecht FM, Siliciano RF, Richman DD, Deeks SG. CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells. Volume 9 of Issue 10. 2014. PMID: 25340755


  139. Kassanjee R, Pilcher CD, Keating SM, Facente SN, McKinney E, Price MA, Martin JN, Little S, Hecht FM, Kallas EG, Welte A, Busch MP, Murphy G. Independent assessment of candidate HIV incidence assays on specimens in the CEPHIA repository. 2014. PMID: 25144218


  140. Norström MM, Veras NM, Huang W, Proper MC, Cook J, Hartogensis W, Hecht FM, Karlsson AC, Karlsoon AC, Salemi M. Baseline CD4+ T cell counts correlates with HIV-1 synonymous rate in HLA-B*5701 subjects with different risk of disease progression. 2014. PMID: 25187947


  141. Klatt NR, Bosinger SE, Peck M, Richert-Spuhler LE, Heigele A, Gile JP, Patel N, Taaffe J, Julg B, Camerini D, Torti C, Martin JN, Deeks SG, Sinclair E, Hecht FM, Lederman MM, Paiardini M, Kirchhoff F, Brenchley JM, Hunt PW, Silvestri G. Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals. Volume 10 of Issue 8. 2014. PMID: 25167059


  142. Streeck H, Lu R, Beckwith N, Milazzo M, Liu M, Routy JP, Little S, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Alter G, Heckerman D, Carrington M, Rosenberg ES, Altfeld M. Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome. 2014. PMID: 25165102


  143. Henje Blom E, Duncan LG, Ho TC, Connolly CG, LeWinn KZ, Chesney M, Hecht FM, Yang TT. The development of an RDoC-based treatment program for adolescent depression: "Training for Awareness, Resilience, and Action" (TARA). 2014. PMID: 25191250


  144. Cockerham LR, Jain V, Sinclair E, Glidden DV, Hartogenesis W, Hatano H, Hunt PW, Martin JN, Pilcher CD, Sekaly R, McCune JM, Hecht FM, Deeks SG. Programmed death-1 expression on CD4? and CD8? T cells in treated and untreated HIV disease. Volume 28 of Issue 12. 2014. PMID: 24871455


  145. Raposo RA, Abdel-Mohsen M, Deng X, Hecht FM, Pilcher CD, Pillai SK, Nixon DF. Dynamic regulation of host restriction factor expression over the course of HIV-1 infection in vivo. Volume 88 of Issue 19. 2014. PMID: 25031350


  146. McDermott KA, Rao MR, Nagarathna R, Murphy EJ, Burke A, Nagendra RH, Hecht FM. A yoga intervention for type 2 diabetes risk reduction: a pilot randomized controlled trial. 2014. PMID: 24980650


  147. Wang C, Abdel-Mohsen M, Strain MC, Lada SM, Yukl S, Cockerham LR, Pilcher CD, Hecht FM, Sinclair E, Liegler T, Richman DD, Deeks SG, Pillai SK. Decreased HIV type 1 transcription in CCR5-?32 heterozygotes during suppressive antiretroviral therapy. Volume 210 of Issue 11. 2014. PMID: 24935955


  148. Gold JA, Grill M, Peterson J, Pilcher C, Lee E, Hecht FM, Fuchs D, Yiannoutsos CT, Price RW, Robertson K, Spudich S. Longitudinal characterization of depression and mood states beginning in primary HIV infection. 2014. PMID: 24385231


  149. Serrano-Villar S, Sainz T, Lee SA, Hunt PW, Sinclair E, Shacklett BL, Ferre AL, Hayes TL, Somsouk M, Hsue PY, Van Natta ML, Meinert CL, Lederman MM, Hatano H, Jain V, Huang Y, Hecht FM, Martin JN, McCune JM, Moreno S, Deeks SG. HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. Volume 10 of Issue 5. 2014. PMID: 24831517


  150. Gurfein BT, Davidenko O, Premenko-Lanier M, Milush JM, Acree M, Dallman MF, Touma C, Palme R, York VA, Fromentin G, Darcel N, Nixon DF, Hecht FM. Environmental enrichment alters splenic immune cell composition and enhances secondary influenza vaccine responses in mice. 2014. PMID: 24687160


  152. Saslow LR, Kim S, Daubenmier JJ, Moskowitz JT, Phinney SD, Goldman V, Murphy EJ, Cox RM, Moran P, Hecht FM. A randomized pilot trial of a moderate carbohydrate diet compared to a very low carbohydrate diet in overweight or obese individuals with type 2 diabetes mellitus or prediabetes. 2014. PMID: 24717684


  153. Lee SA, Sinclair E, Jain V, Huang Y, Epling L, Van Natta M, Meinert CL, Martin JN, McCune JM, Deeks SG, Lederman MM, Hecht FM, Hunt PW. Low proportions of CD28- CD8+ T cells expressing CD57 can be reversed by early ART initiation and predict mortality in treated HIV infection. Volume 210 of Issue 3. 2014. PMID: 24585893


  154. Lee SA, Sinclair E, Hatano H, Hsue PY, Epling L, Hecht FM, Bangsberg DR, Martin JN, McCune JM, Deeks SG, Hunt PW. Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging. Volume 9 of Issue 2. 2014. PMID: 24586783


  155. Michaud HA, de Mulder M, SenGupta D, Deeks SG, Martin JN, Pilcher CD, Hecht FM, Sacha JB, Nixon DF. Trans-activation, post-transcriptional maturation, and induction of antibodies to HERV-K (HML-2) envelope transmembrane protein in HIV-1 infection. 2014. PMID: 24472118


  156. Milush JM, López-Vergès S, York VA, Deeks SG, Martin JN, Hecht FM, Lanier LL, Nixon DF. CD56negCD16⁺ NK cells are activated mature NK cells with impaired effector function during HIV-1 infection. 2013. PMID: 24351015


  157. Dhruva A, Hecht FM, Miaskowski C, Kaptchuk TJ, Bodeker G, Abrams D, Lad V, Adler SR. Correlating traditional Ayurvedic and modern medical perspectives on cancer: results of a qualitative study. 2013. PMID: 24341342


  158. Pilcher CD, Louie B, Facente S, Keating S, Hackett J, Vallari A, Hall C, Dowling T, Busch MP, Klausner JD, Hecht FM, Liska S, Pandori MW. Performance of rapid point-of-care and laboratory tests for acute and established HIV infection in San Francisco. 2013. PMID: 24349007


  159. Daubenmier J, Lustig RH, Hecht FM, Kristeller J, Woolley J, Adam T, Dallman M, Epel E. A new biomarker of hedonic eating? A preliminary investigation of cortisol and nausea responses to acute opioid blockade. 2013. PMID: 24291355


  160. Josefsson L, von Stockenstrom S, Faria NR, Sinclair E, Bacchetti P, Killian M, Epling L, Tan A, Ho T, Lemey P, Shao W, Hunt PW, Somsouk M, Wylie W, Douek DC, Loeb L, Custer J, Hoh R, Poole L, Deeks SG, Hecht F, Palmer S. The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time. Volume 110 of Issue 51. 2013. PMID: 24277811


  161. Vaidya SA, Streeck H, Beckwith N, Ghebremichael M, Pereyra F, Kwon DS, Addo MM, Rychert J, Routy JP, Jessen H, Kelleher AD, Hecht F, Sekaly RP, Carrington M, Walker BD, Allen TM, Rosenberg ES, Altfeld M. Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection. 2013. PMID: 24245727


  162. Ooms M, Brayton B, Letko M, Maio SM, Pilcher CD, Hecht FM, Barbour JD, Simon V. HIV-1 Vif adaptation to human APOBEC3H haplotypes. 2013. PMID: 24139399


  164. Patterson S, Moran P, Epel E, Sinclair E, Kemeny ME, Deeks SG, Bacchetti P, Acree M, Epling L, Kirschbaum C, Hecht FM. Cortisol patterns are associated with T cell activation in HIV. 2013. PMID: 23922644


  165. Jain V, Hartogensis W, Bacchetti P, Hunt PW, Hatano H, Sinclair E, Epling L, Lee TH, Busch MP, McCune JM, Pilcher CD, Hecht FM, Deeks SG. Antiretroviral therapy initiated within 6 months of HIV infection is associated with lower T-cell activation and smaller HIV reservoir size. Volume 208 of Issue 8. 2013. PMID: 23852127


  166. Champiat S, Garrison KE, Raposo RA, Burwitz BJ, Reed J, Tandon R, York VA, Newman LP, Nimityongskul FA, Wilson NA, Almeida RR, Martin JN, Deeks SG, Rosenberg MG, Wiznia AA, Spotts GE, Pilcher CD, Hecht FM, Ostrowski MA, Sacha JB, Nixon DF. T cells target APOBEC3 proteins in human immunodeficiency virus type 1-infected humans and simian immunodeficiency virus-infected Indian rhesus macaques. 2013. PMID: 23536679


  167. Eriksson S, Graf EH, Dahl V, Strain MC, Yukl SA, Lysenko ES, Bosch RJ, Lai J, Chioma S, Emad F, Abdel-Mohsen M, Hoh R, Hecht F, Hunt P, Somsouk M, Wong J, Johnston R, Siliciano RF, Richman DD, O'Doherty U, Palmer S, Deeks SG, Siliciano JD. Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies. Volume 9 of Issue 2. 2013. PMID: 23459007


  168. Vallabhaneni S, McConnell JJ, Loeb L, Hartogensis W, Hecht FM, Grant RM, Pilcher CD. Changes in seroadaptive practices from before to after diagnosis of recent HIV infection among men who have sex with men. 2013. PMID: 23405145


  169. Perez CL, Milush JM, Buggert M, Eriksson EM, Larsen MV, Liegler T, Hartogensis W, Bacchetti P, Lund O, Hecht FM, Nixon DF, Karlsson AC. Targeting of conserved gag-epitopes in early HIV infection is associated with lower plasma viral load and slower CD4(+) T cell depletion. 2013. PMID: 23140171


  171. Hatano H, Jain V, Hunt PW, Lee TH, Sinclair E, Do TD, Hoh R, Martin JN, McCune JM, Hecht F, Busch MP, Deeks SG. Cell-based measures of viral persistence are associated with immune activation and programmed cell death protein 1 (PD-1)-expressing CD4+ T cells. Volume 208 of Issue 1. 2012. PMID: 23089590


  172. Norström MM, Buggert M, Tauriainen J, Hartogensis W, Prosperi MC, Wallet MA, Hecht FM, Salemi M, Karlsson AC. Combination of immune and viral factors distinguishes low-risk versus high-risk HIV-1 disease progression in HLA-B*5701 subjects. 2012. PMID: 22761389


  173. Champiat S, Raposo RA, Maness NJ, Lehman JL, Purtell SE, Hasenkrug AM, Miller JC, Dean H, Koff WC, Hong MA, Martin JN, Deeks SG, Spotts GE, Pilcher CD, Hecht FM, Kallas EG, Garrison KE, Nixon DF. Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection. 2012. PMID: 22768072


  174. Ho JE, Scherzer R, Hecht FM, Maka K, Selby V, Martin JN, Ganz P, Deeks SG, Hsue PY. The association of CD4+ T-cell counts and cardiovascular risk in treated HIV disease. 2012. PMID: 22382147


  175. Gurfein BT, Stamm AW, Bacchetti P, Dallman MF, Nadkarni NA, Milush JM, Touma C, Palme R, Di Borgo CP, Fromentin G, Lown-Hecht R, Konsman JP, Acree M, Premenko-Lanier M, Darcel N, Hecht FM, Nixon DF. The calm mouse: an animal model of stress reduction. 2012. PMID: 22398685


  176. Josefsson L, Eriksson S, Sinclair E, Ho T, Killian M, Epling L, Shao W, Lewis B, Bacchetti P, Loeb L, Custer J, Poole L, Hecht FM, Palmer S. Hematopoietic precursor cells isolated from patients on long-term suppressive HIV therapy did not contain HIV-1 DNA. 2012. PMID: 22536001


  177. Dhruva A, Miaskowski C, Abrams D, Acree M, Cooper B, Goodman S, Hecht FM. Yoga breathing for cancer chemotherapy-associated symptoms and quality of life: results of a pilot randomized controlled trial. 2012. PMID: 22525009


  178. Mehling WE, Gopisetty V, Bartmess E, Acree M, Pressman A, Goldberg H, Hecht FM, Carey T, Avins AL. The prognosis of acute low back pain in primary care in the United States: a 2-year prospective cohort study. 2012. PMID: 22504516


  179. Mehling WE, Lown EA, Dvorak CC, Cowan MJ, Horn BN, Dunn EA, Acree M, Abrams DI, Hecht FM. Hematopoietic cell transplant and use of massage for improved symptom management: results from a pilot randomized control trial. 2012. PMID: 22454665


  180. Mehling WE, Gopisetty V, Acree M, Pressman A, Carey T, Goldberg H, Hecht FM, Avins AL. Acute low back pain and primary care: how to define recovery and chronification? 2011. PMID: 21311400


  181. Daubenmier J, Lin J, Blackburn E, Hecht FM, Kristeller J, Maninger N, Kuwata M, Bacchetti P, Havel PJ, Epel E. Changes in stress, eating, and metabolic factors are related to changes in telomerase activity in a randomized mindfulness intervention pilot study. 2011. PMID: 22169588


  182. Eriksson EM, Milush JM, Ho EL, Batista MD, Holditch SJ, Keh CE, Norris PJ, Keating SM, Deeks SG, Hunt PW, Martin JN, Rosenberg MG, Hecht FM, Nixon DF. Expansion of CD8+ T cells lacking Sema4D/CD100 during HIV-1 infection identifies a subset of T cells with decreased functional capacity. Volume 119 of Issue 3. 2011. PMID: 22134167


  183. Daubenmier J, Kristeller J, Hecht FM, Maninger N, Kuwata M, Jhaveri K, Lustig RH, Kemeny M, Karan L, Epel E. Mindfulness Intervention for Stress Eating to Reduce Cortisol and Abdominal Fat among Overweight and Obese Women: An Exploratory Randomized Controlled Study. 2011. PMID: 21977314


  184. Crawford TQ, Ndhlovu LC, Tan A, Carvidi A, Hecht FM, Sinclair E, Barbour JD. HIV-1 infection abrogates CD8+ T cell mitogen-activated protein kinase signaling responses. 2011. PMID: 21937661


  185. Duncan LG, Moskowitz JT, Neilands TB, Dilworth SE, Hecht FM, Johnson MO. Mindfulness-based stress reduction for HIV treatment side effects: a randomized, wait-list controlled trial. 2011. PMID: 21925831


  186. Spudich S, Gisslen M, Hagberg L, Lee E, Liegler T, Brew B, Fuchs D, Tambussi G, Cinque P, Hecht FM, Price RW. Central nervous system immune activation characterizes primary human immunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burden. 2011. PMID: 21844301


  187. Hecht FM, Wellman R, Busch MP, Pilcher CD, Norris PJ, Margolick JB, Collier AC, Little SJ, Markowitz M, Routy JP, Holte S. Identifying the early post-HIV antibody seroconversion period. 2011. PMID: 21791654


  188. SenGupta D, Tandon R, Vieira RG, Ndhlovu LC, Lown-Hecht R, Ormsby CE, Loh L, Jones RB, Garrison KE, Martin JN, York VA, Spotts G, Reyes-Terán G, Ostrowski MA, Hecht FM, Deeks SG, Nixon DF. Strong human endogenous retrovirus-specific T cell responses are associated with control of HIV-1 in chronic infection. 2011. PMID: 21525339


  189. Jain V, Sucupira MC, Bacchetti P, Hartogensis W, Diaz RS, Kallas EG, Janini LM, Liegler T, Pilcher CD, Grant RM, Cortes R, Deeks SG, Hecht FM. Differential persistence of transmitted HIV-1 drug resistance mutation classes. 2011. PMID: 21451005


  190. Kuylenstierna C, Snyder-Cappione JE, Loo CP, Long BR, Gonzalez VD, Michaëlsson J, Moll M, Spotts G, Hecht FM, Nixon DF, Sandberg JK. NK cells and CD1d-restricted NKT cells respond in different ways with divergent kinetics to IL-2 treatment in primary HIV-1 infection. 2011. PMID: 21198755


  191. Favre D, Stoddart CA, Emu B, Hoh R, Martin JN, Hecht FM, Deeks SG, McCune JM. HIV disease progression correlates with the generation of dysfunctional naive CD8(low) T cells. 2011. PMID: 21200021


  192. Gourraud PA, Karaouni A, Woo JM, Schmidt T, Oksenberg JR, Hecht FM, Liegler TJ, Barbour JD. APOBEC3H haplotypes and HIV-1 pro-viral vif DNA sequence diversity in early untreated human immunodeficiency virus-1 infection. 2010. PMID: 21167246


  193. Jain V, Liegler T, Vittinghoff E, Hartogensis W, Bacchetti P, Poole L, Loeb L, Pilcher CD, Grant RM, Deeks SG, Hecht FM. Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009. 2010. PMID: 21170322


  195. D'Souza MP, Axten KL, Hecht FM, Altfeld M. Acute HIV-1 infection: what's new? Where are we going? 2010. PMID: 20846032


  196. Cohen MS, Gay CL, Busch MP, Hecht FM. The detection of acute HIV infection. 2010. PMID: 20846033


  198. Ndhlovu LC, Sinclair E, Epling L, Tan QX, Ho T, Jha AR, Eccles-James I, Tincati C, Levy JA, Nixon DF, Hecht FM, Barbour JD. IL-2 immunotherapy to recently HIV-1 infected adults maintains the numbers of IL-17 expressing CD4+ T (T(H)17) cells in the periphery. 2010. PMID: 20571894


  199. Favre D, Mold J, Hunt PW, Kanwar B, Loke P, Seu L, Barbour JD, Lowe MM, Jayawardene A, Aweeka F, Huang Y, Douek DC, Brenchley JM, Martin JN, Hecht FM, Deeks SG, McCune JM. Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease. Volume 2 of Issue 32. 2010. PMID: 20484731


  200. Markowitz M, Vaida F, Hare CB, Boden D, Mohri H, Hecht FM, Kalayjian RC, Conrad A, Mildvan D, Aberg J, Hogan C, Kilby JM, Balfour HH, Schafer K, Richman D, Little S. The virologic and immunologic effects of cyclosporine as an adjunct to antiretroviral therapy in patients treated during acute and early HIV-1 infection. 2010. PMID: 20235838


  201. Hecht FM, Hartogensis W, Bragg L, Bacchetti P, Atchison R, Grant R, Barbour J, Deeks SG. HIV RNA level in early infection is predicted by viral load in the transmission source. 2010. PMID: 20168202


  202. Willberg CB, Garrison KE, Jones RB, Meiklejohn DA, Spotts G, Liegler TJ, Ostrowski MA, Karlsson AC, Hecht FM, Nixon DF. Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes. 2010. PMID: 20422053


  203. Naeger DM, Martin JN, Sinclair E, Hunt PW, Bangsberg DR, Hecht F, Hsue P, McCune JM, Deeks SG. Cytomegalovirus-specific T cells persist at very high levels during long-term antiretroviral treatment of HIV disease. Volume 5 of Issue 1. 2010. PMID: 20126452


  204. Schweighardt B, Wrin T, Meiklejohn DA, Spotts G, Petropoulos CJ, Nixon DF, Hecht FM. Immune escape mutations detected within HIV-1 epitopes associated with viral control during treatment interruption. 2010. PMID: 19910798


  205. Khurana S, Norris PJ, Busch MP, Haynes BF, Park S, Sasono P, Mlisana K, Salim AK, Hecht FM, Mulenga J, Chomba E, Hunter E, Allen S, Nemo G, Rodriguez-Chavez IR, Women's Interagency HIV Study Collaborative Study Group, Margolick JB, Multicenter AIDS Cohort Study (MACS), Golding H. HIV-Selectest enzyme immunoassay and rapid test: ability to detect seroconversion following HIV-1 infection. 2009. PMID: 19906903


  206. Snyder-Cappione JE, Loo CP, Carvalho KI, Kuylenstierna C, Deeks SG, Hecht FM, Rosenberg MG, Sandberg JK, Kallas EG, Nixon DF. Lower cytokine secretion ex vivo by natural killer T cells in HIV-infected individuals is associated with higher CD161 expression. 2009. PMID: 19590406


  207. Huang W, Toma J, Stawiski E, Fransen S, Wrin T, Parkin N, Whitcomb JM, Coakley E, Hecht FM, Deeks SG, Gandhi RT, Eshleman SH, Petropoulos CJ. Characterization of human immunodeficiency virus type 1 populations containing CXCR4-using variants from recently infected individuals. 2009. PMID: 19678765


  208. Garrison KE, Champiat S, York VA, Agrawal AT, Kallas EG, Martin JN, Hecht FM, Deeks SG, Nixon DF. Transcriptional errors in human immunodeficiency virus type 1 generate targets for T-cell responses. 2009. PMID: 19571107


  210. Streeck H, Jolin JS, Qi Y, Yassine-Diab B, Johnson RC, Kwon DS, Addo MM, Brumme C, Routy JP, Little S, Jessen HK, Kelleher AD, Hecht FM, Sekaly RP, Rosenberg ES, Walker BD, Carrington M, Altfeld M. Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells. 2009. PMID: 19458000


  211. Mehling WE, Gopisetty V, Daubenmier J, Price CJ, Hecht FM, Stewart A. Body awareness: construct and self-report measures. 2009. PMID: 19440300


  212. Kelley CF, Kitchen CM, Hunt PW, Rodriguez B, Hecht FM, Kitahata M, Crane HM, Willig J, Mugavero M, Saag M, Martin JN, Deeks SG. Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment. Volume 48 of Issue 6. 2009. PMID: 19193107


  213. Apuzzo LG, Vaida F, Gallant JE, Ernstrom KB, Little SJ, Routy JP, Collier AC, Conway B, Markowitz MH, Hecht FM, Walker BD, Connick E, Margolick JB. Tolerability and efficacy of PI versus NNRTI-based regimens in subjects receiving HAART during acute or early HIV infection. 2009. PMID: 19194317


  214. Barbour JD, Ndhlovu LC, Xuan Tan Q, Ho T, Epling L, Bredt BM, Levy JA, Hecht FM, Sinclair E. High CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication. 2009. PMID: 19198651


  215. Killian MS, Roop J, Ng S, Hecht FM, Levy JA. CD8+ cell anti-HIV activity rapidly increases upon discontinuation of early antiretroviral therapy. 2009. PMID: 19189205


  216. Jones RB, Ndhlovu LC, Barbour JD, Sheth PM, Jha AR, Long BR, Wong JC, Satkunarajah M, Schweneker M, Chapman JM, Gyenes G, Vali B, Hyrcza MD, Yue FY, Kovacs C, Sassi A, Loutfy M, Halpenny R, Persad D, Spotts G, Hecht FM, Chun TW, McCune JM, Kaul R, Rini JM, Nixon DF, Ostrowski MA. Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. 2008. PMID: 19001139


  217. Willberg CB, McConnell JJ, Eriksson EM, Bragg LA, York VA, Liegler TJ, Hecht FM, Grant RM, Nixon DF. Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus. 2008. PMID: 18949024


  218. Owotade FJ, Shiboski CH, Poole L, Ramstead CA, Malvin K, Hecht FM, Greenspan JS. Prevalence of oral disease among adults with primary HIV infection. 2008. PMID: 18826380


  219. Carrico AW, Johnson MO, Morin SF, Remien RH, Riley ED, Hecht FM, Fuchs D. Stimulant use is associated with immune activation and depleted tryptophan among HIV-positive persons on anti-retroviral therapy. 2008. PMID: 18703133


  220. Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM. Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance. 2008. PMID: 18427201


  221. Ahuja SK, Kulkarni H, Catano G, Agan BK, Camargo JF, He W, O'Connell RJ, Marconi VC, Delmar J, Eron J, Clark RA, Frost S, Martin J, Ahuja SS, Deeks SG, Little S, Richman D, Hecht FM, Dolan MJ. CCL3L1-CCR5 genotype influences durability of immune recovery during antiretroviral therapy of HIV-1-infected individuals. 2008. PMID: 18376407


  222. Long BR, Ndhlovu LC, Oksenberg JR, Lanier LL, Hecht FM, Nixon DF, Barbour JD. Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection. 2008. PMID: 18305035


  223. Louie B, Wong E, Klausner JD, Liska S, Hecht F, Dowling T, Obeso M, Phillips SS, Pandori MW. Assessment of rapid tests for detection of human immunodeficiency virus-specific antibodies in recently infected individuals. 2008. PMID: 18234875


  224. Daar ES, Pilcher CD, Hecht FM. Clinical presentation and diagnosis of primary HIV-1 infection. 2008. PMID: 19372938


  225. Michaëlsson J, Long BR, Loo CP, Lanier LL, Spotts G, Hecht FM, Nixon DF. Immune reconstitution of CD56(dim) NK cells in individuals with primary HIV-1 infection treated with interleukin-2. 2008. PMID: 18171294


  226. Long BR, Michaelsson J, Loo CP, Ballan WM, Vu BA, Hecht FM, Lanier LL, Chapman JM, Nixon DF. Elevated frequency of gamma interferon-producing NK cells in healthy adults vaccinated against influenza virus. 2007. PMID: 18003818


  228. Garrison KE, Jones RB, Meiklejohn DA, Anwar N, Ndhlovu LC, Chapman JM, Erickson AL, Agrawal A, Spotts G, Hecht FM, Rakoff-Nahoum S, Lenz J, Ostrowski MA, Nixon DF. T cell responses to human endogenous retroviruses in HIV-1 infection. 2007. PMID: 17997601


  229. Dolan MJ, Kulkarni H, Camargo JF, He W, Smith A, Anaya JM, Miura T, Hecht FM, Mamtani M, Pereyra F, Marconi V, Mangano A, Sen L, Bologna R, Clark RA, Anderson SA, Delmar J, O'Connell RJ, Lloyd A, Martin J, Ahuja SS, Agan BK, Walker BD, Deeks SG, Ahuja SK. CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms. 2007. PMID: 17952079


  230. Owen RE, Sinclair E, Emu B, Heitman JW, Hirschkorn DF, Epling CL, Tan QX, Custer B, Harris JM, Jacobson MA, McCune JM, Martin JN, Hecht FM, Deeks SG, Norris PJ. Loss of T cell responses following long-term cryopreservation. 2007. PMID: 17707394


  233. Fryer JF, Delwart E, Hecht FM, Bernardin F, Jones MS, Shah N, Baylis SA. Frequent detection of the parvoviruses, PARV4 and PARV5, in plasma from blood donors and symptomatic individuals. 2007. PMID: 17524097


  234. Sriram U, Wong M, Caillier SJ, Hecht FM, Elkins MK, Levy JA, Oksenberg JR, Baranzini SE. Quantitative longitudinal analysis of T cell receptor repertoire expression in HIV-infected patients on antiretroviral and interleukin-2 therapy. 2007. PMID: 17531001


  235. Barbour JD, Sriram U, Caillier SJ, Levy JA, Hecht FM, Oksenberg JR. Synergy or independence? Deciphering the interaction of HLA Class I and NK cell KIR alleles in early HIV-1 disease progression. 2007. PMID: 17447840


  237. Hecht FM, Wolf LE, Lo B. Lessons from an HIV transmission pair. 2007. PMID: 17396989


  238. Mehling WE, Jacobs B, Acree M, Wilson L, Bostrom A, West J, Acquah J, Burns B, Chapman J, Hecht FM. Symptom management with massage and acupuncture in postoperative cancer patients: a randomized controlled trial. 2007. PMID: 17349495


  239. Karlsson AC, Iversen AK, Chapman JM, de Oliviera T, Spotts G, McMichael AJ, Davenport MP, Hecht FM, Nixon DF. Sequential broadening of CTL responses in early HIV-1 infection is associated with viral escape. 2007. PMID: 17311088


  240. Hecht F, Pilcher C. Lessons from primary HIV infection. 2007. PMID: 17549830


  241. Colfax GN, Vittinghoff E, Grant R, Lum P, Spotts G, Hecht FM. Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance. 2007. PMID: 17197817


  243. Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC. Microbial translocation is a cause of systemic immune activation in chronic HIV infection. 2006. PMID: 17115046


  244. Barbour JD, Hecht FM, Little SJ, Markowitz M, Daar ES, Kelleher AD, Routy JP, Campbell TB, Rosenberg ES, Segal MR, Weidler J, Grant RM. Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity. 2006. PMID: 17053362


  245. Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V. Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo. Volume 80 of Issue 21. 2006. PMID: 16956949


  246. Hecht FM, Wang L, Collier A, Little S, Markowitz M, Margolick J, Kilby JM, Daar E, Conway B, Holte S, AIEDRP Network. A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection. 2006. PMID: 16941337


  247. Norris PJ, Pappalardo BL, Custer B, Spotts G, Hecht FM, Busch MP. Elevations in IL-10, TNF-alpha, and IFN-gamma from the earliest point of HIV Type 1 infection. 2006. PMID: 16910831


  248. Hecht FM. A piece of my mind. The CBC. 2006. PMID: 16835410


  249. Killian MS, Norris PJ, Rawal BD, Lebedeva M, Hecht FM, Levy JA, Busch MP. The effects of early antiretroviral therapy and its discontinuation on the HIV-specific antibody response. 2006. PMID: 16831088


  251. Deeks SG, Schweighardt B, Wrin T, Galovich J, Hoh R, Sinclair E, Hunt P, McCune JM, Martin JN, Petropoulos CJ, Hecht FM. Neutralizing antibody responses against autologous and heterologous viruses in acute versus chronic human immunodeficiency virus (HIV) infection: evidence for a constraint on the ability of HIV to completely evade neutralizing antibody responses. Volume 80 of Issue 12. 2006. PMID: 16731954


  252. Chin-Hong PV, Hecht FM, Klausner JD. Newly diagnosed HIV infection. 2006. PMID: 16481652


  253. Hare CB, Pappalardo BL, Busch MP, Karlsson AC, Phelps BH, Alexander SS, Bentsen C, Ramstead CA, Nixon DF, Levy JA, Hecht FM. Seroreversion in subjects receiving antiretroviral therapy during acute/early HIV infection. 2006. PMID: 16447118


  254. Moll M, Snyder-Cappione J, Spotts G, Hecht FM, Sandberg JK, Nixon DF. Expansion of CD1d-restricted NKT cells in patients with primary HIV-1 infection treated with interleukin-2. 2005. PMID: 16368878


  255. Roland ME, Neilands TB, Krone MR, Katz MH, Franses K, Grant RM, Busch MP, Hecht FM, Shacklett BL, Kahn JO, Bamberger JD, Coates TJ, Chesney MA, Martin JN. Seroconversion following nonoccupational postexposure prophylaxis against HIV. 2005. PMID: 16231265


  256. Lennette ET, Busch MP, Hecht FM, Levy JA. Potential herpesvirus interaction during HIV type 1 primary infection. 2005. PMID: 16225414


  259. Jones MS, Kapoor A, Lukashov VV, Simmonds P, Hecht F, Delwart E. New DNA viruses identified in patients with acute viral infection syndrome. 2005. PMID: 15956568


  260. Mehling WE, Hamel KA, Acree M, Byl N, Hecht FM. Randomized, controlled trial of breath therapy for patients with chronic low-back pain. 2005. PMID: 16053121


  261. Mehling WE, DiBlasi Z, Hecht F. Bias control in trials of bodywork: a review of methodological issues. 2005. PMID: 15865501


  262. Elkins MK, Vittinghoff E, Baranzini SE, Hecht FM, Sriram U, Busch MP, Levy JA, Oksenberg JR, San Francisco Primary Infection Group. Longitudinal analysis of B cell repertoire and antibody gene rearrangements during early HIV infection. 2005. PMID: 15538390


  263. Martinez-Mariño B, Shiboski S, Hecht FM, Kahn JO, Levy JA. Interleukin-2 therapy restores CD8 cell non-cytotoxic anti-HIV responses in primary infection subjects receiving HAART. 2004. PMID: 15577620


  264. Barbour JD, Hecht FM, Wrin T, Liegler TJ, Ramstead CA, Busch MP, Segal MR, Petropoulos CJ, Grant RM. Persistence of primary drug resistance among recently HIV-1 infected adults. 2004. PMID: 15280779


  265. Aandahl EM, Quigley MF, Moretto WJ, Moll M, Gonzalez VD, Sönnerborg A, Lindbäck S, Hecht FM, Deeks SG, Rosenberg MG, Nixon DF, Sandberg JK. Expansion of CD7(low) and CD7(negative) CD8 T-cell effector subsets in HIV-1 infection: correlation with antigenic load and reversion by antiretroviral treatment. 2004. PMID: 15308569


  266. Barbour JD, Hecht FM, Wrin T, Segal MR, Ramstead CA, Liegler TJ, Busch MP, Petropoulos CJ, Hellmann NS, Kahn JO, Grant RM. Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naive adults in early HIV-1 infection. 2004. PMID: 15216458


  267. Deeks SG, Kitchen CM, Liu L, Guo H, Gascon R, Narváez AB, Hunt P, Martin JN, Kahn JO, Levy J, McGrath MS, Hecht FM. Immune activation set point during early HIV infection predicts subsequent CD4+ T-cell changes independent of viral load. Volume 104 of Issue 4. 2004. PMID: 15117761


  268. Martinez-Mariño B, Ashlock BM, Shiboski S, Hecht FM, Levy JA. Effect of IL-2 therapy on CD8+ cell noncytotoxic anti-HIV response during primary HIV-1 infection. 2004. PMID: 15024180


  269. Aandahl EM, Michaëlsson J, Moretto WJ, Hecht FM, Nixon DF. Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens. 2004. PMID: 14963140


  270. Altfeld M, Addo MM, Rosenberg ES, Hecht FM, Lee PK, Vogel M, Yu XG, Draenert R, Johnston MN, Strick D, Allen TM, Feeney ME, Kahn JO, Sekaly RP, Levy JA, Rockstroh JK, Goulder PJ, Walker BD. Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection. 2003. PMID: 14685052


  271. Rawal BD, Degula A, Lebedeva L, Janssen RS, Hecht FM, Sheppard HW, Busch MP. Development of a new less-sensitive enzyme immunoassay for detection of early HIV-1 infection. 2003. PMID: 12843746


  272. Jacobson MA, Liu L, Khayam-Bashi H, Deeks SG, Hecht FM, Kahn J. Absolute or total lymphocyte count as a marker for the CD4 T lymphocyte criterion for initiating antiretroviral therapy. 2003. PMID: 12660541


  273. Smith DE, Kaufmann GR, Kahn JO, Hecht FM, Grey PA, Zaunders JJ, Cunningham PH, Carr A, Duncombe C, Quan DC, Petersen A, Cooper DA. Greater reversal of CD4+ cell abnormalities and viral load reduction after initiation of antiretroviral therapy with zidovudine, lamivudine, and nelfinavir before complete HIV type 1 seroconversion. 2003. PMID: 12689411


  274. Lansky A, Lehman JS, Gatwood J, Hecht FM, Fleming PL. Changes in HIV testing after implementation of name-based HIV case surveillance in New Mexico. 2002. PMID: 12406803


  275. Kellerman SE, Lehman JS, Lansky A, Stevens MR, Hecht FM, Bindman AB, Wortley PM. HIV testing within at-risk populations in the United States and the reasons for seeking or avoiding HIV testing. 2002. PMID: 12394799


  276. Colfax GN, Lehman JS, Bindman AB, Vittinghoff E, Vranizan K, Fleming PL, Chesney M, Osmond D, Hecht FM, Multisite Evaluation of Surveillance of HIV (MESH) Study Group. What happened to home HIV test collection kits? Intent to use kits, actual use, and barriers to use among persons at risk for HIV infection. 2002. PMID: 12419117


  277. Grant RM, Hecht FM, Warmerdam M, Liu L, Liegler T, Petropoulos CJ, Hellmann NS, Chesney M, Busch MP, Kahn JO. Time trends in primary HIV-1 drug resistance among recently infected persons. 2002. PMID: 12095382


  279. Hecht FM, Busch MP, Rawal B, Webb M, Rosenberg E, Swanson M, Chesney M, Anderson J, Levy J, Kahn JO. Use of laboratory tests and clinical symptoms for identification of primary HIV infection. 2002. PMID: 12004270


  280. Boswell SL, Hecht FM, Powderly WG, Soloway B, Volberding PA. HIV expertise: a roundtable. 2001. PMID: 11547599


  281. Day CL, Shea AK, Altfeld MA, Olson DP, Buchbinder SP, Hecht FM, Rosenberg ES, Walker BD, Kalams SA. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. 2001. PMID: 11413294


  284. Bangsberg DR, Hecht FM, Clague H, Charlebois ED, Ciccarone D, Chesney M, Moss A. Provider assessment of adherence to HIV antiretroviral therapy. 2001. PMID: 11391162


  285. Altfeld M, Rosenberg ES, Shankarappa R, Mukherjee JS, Hecht FM, Eldridge RL, Addo MM, Poon SH, Phillips MN, Robbins GK, Sax PE, Boswell S, Kahn JO, Brander C, Goulder PJ, Levy JA, Mullins JI, Walker BD. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. 2001. PMID: 11148221


  286. Stranford SA, Ong JC, Martinez-Marino B, Busch M, Hecht FM, Kahn J, Levy JA. Reduction in CD8+ cell noncytotoxic anti-HIV activity in individuals receiving highly active antiretroviral therapy during primary infection. 2001. PMID: 11136234


  288. Huang L, Hecht FM. Why does Pneumocystis carinii pneumonia still occur? 2000. PMID: 11101076


  289. Hecht FM, Chesney MA, Lehman JS, Osmond D, Vranizan K, Colman S, Keane D, Reingold A, Bindman AB. Does HIV reporting by name deter testing? MESH Study Group. 2000. PMID: 10985318


  290. Bangsberg DR, Hecht FM, Charlebois ED, Zolopa AR, Holodniy M, Sheiner L, Bamberger JD, Chesney MA, Moss A. Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population. 2000. PMID: 10770537


  292. Osmond DH, Bindman AB, Vranizan K, Lehman JS, Hecht FM, Keane D, Reingold A. Name-based surveillance and public health interventions for persons with HIV infection. Multistate Evaluation of Surveillance for HIV Study Group. 1999. PMID: 10577302


  293. Hecht FM, Wilson IB, Wu AW, Cook RL, Turner BJ. Optimizing care for persons with HIV infection. Society of General Internal Medicine AIDS Task Force. 1999. PMID: 10419430


  294. Saag M, Hecht F. Antiretrovirals for HIV nephropathy? 1999. PMID: 11366883


  295. Deeks SG, Hecht FM, Swanson M, Elbeik T, Loftus R, Cohen PT, Grant RM. HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: response to both initial and salvage therapy. 1999. PMID: 10397555


  296. Chesney MA, Ickovics J, Hecht FM, Sikipa G, Rabkin J. Adherence: a necessity for successful HIV combination therapy. 1999. PMID: 10885784


  298. Bindman AB, Osmond D, Hecht FM, Lehman JS, Vranizan K, Keane D, Reingold A. Multistate evaluation of anonymous HIV testing and access to medical care. Multistate Evaluation of Surveillance of HIV (MESH) Study Group. 1998. PMID: 9801001


  300. Hecht FM, Grant RM, Petropoulos CJ, Dillon B, Chesney MA, Tian H, Hellmann NS, Bandrapalli NI, Digilio L, Branson B, Kahn JO. Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors. 1998. PMID: 9682043


  301. Janssen RS, Satten GA, Stramer SL, Rawal BD, O'Brien TR, Weiblen BJ, Hecht FM, Jack N, Cleghorn FR, Kahn JO, Chesney MA, Busch MP. New testing strategy to detect early HIV-1 infection for use in incidence estimates and for clinical and prevention purposes. 1998. PMID: 9660362


  302. Hecht FM, Wheat J, Korzun AH, Hafner R, Skahan KJ, Larsen R, Limjoco MT, Simpson M, Schneider D, Keefer MC, Clark R, Lai KK, Jacobson JM, Squires K, Bartlett JA, Powderly W. Itraconazole maintenance treatment for histoplasmosis in AIDS: a prospective, multicenter trial. 1997. PMID: 9358104


  303. Bangsberg D, Tulsky JP, Hecht FM, Moss AR. Protease inhibitors in the homeless. 1997. PMID: 9207341


  305. Hecht F. A new focus on primary HIV infection. 1996. PMID: 11363761


  306. Hecht BK, Hecht F. Murder of son with a genital malformation. 1995. PMID: 8533853


  307. Huang L, Hecht FM, Stansell JD, Montanti R, Hadley WK, Hopewell PC. Suspected Pneumocystis carinii pneumonia with a negative induced sputum examination. Is early bronchoscopy useful? 1995. PMID: 7767533


  309. Jewett JF, Hecht FM. Preventive health care for adults with HIV infection. 1993. PMID: 8433470


  310. Hecht FM. H. influenzae vaccines in HIV. 1992. PMID: 1579147


  311. Hecht FM. Diarrhea and AIDS. 1990. PMID: 2240886


  312. Hecht F. The quality and influence of JAMA. 1988. PMID: 3346975


  313. Smith SD, Morgan R, Gemmell R, Amylon MD, Link MP, Linker C, Hecht BK, Warnke R, Glader BE, Hecht F. Clinical and biologic characterization of T-cell neoplasias with rearrangements of chromosome 7 band q34. 1988. PMID: 2962650


  314. Zaccaria A, Alimena G, Billström R, Carbonell F, Castoldi GL, Fuscaldo K, Gastaldi R, Hecht F, Mitelman F, Hossfeld DK. A cytogenetical analysis in patients with secondary hematological disorders. 1987. PMID: 3127298


  315. Liu E, Hjelle B, Morgan R, Hecht F, Bishop JM. Mutations of the Kirsten-ras proto-oncogene in human preleukaemia. 1987. PMID: 3313061


  316. Radvany RM, Schubert MS, Kiamar M, Jarzabek V, Koehler-Carone K, Kuban D, Hecht F. Lymphocyte subpopulation profiles and mitogen kinetics in immunological deficiency testing. 1987. PMID: 2956275


  318. Zaccaria A, Alimena G, Baccarani M, Billström R, Carbonell F, Castoldi GL, Fuscaldo K, Hecht F, Hossfeld DK, Mitelman F. Cytogenetic analyses in 89 patients with secondary hematologic disorders--results of a cooperative study. 1987. PMID: 3828975


  319. Hecht F. "I accuse" the Journal of unfair journalism. 1987. PMID: 3821816


  321. Smith SD, Link MP, Trela M, Amylon M, Sklar J, Morgan R, Hecht F. Chromosome 9 abnormalities in childhood T-cell leukemia. 1986. PMID: 3487732


  322. Morgan R, Hecht BK, Sandberg AA, Hecht F, Smith SD. Chromosome 5q35 breakpoint in malignant histiocytosis. 1986. PMID: 3702936


  326. Hecht F, Morgan R, Gemmill RM, Hecht BK. Translocations in T-cell leukemia in lymphoma. 1985. PMID: 3875794


  327. Hecht F, Hecht BK, Bixenman HA. Caution about chorionic villi sampling in the first trimester. 1984. PMID: 6717512


  329. Hecht F, Kaiser-McCaw B. Immunoglobulin expression in Burkitt's lymphoma and leukemia. 1982. PMID: 6958975


  331. Clewell WH, Johnson ML, Meier PR, Newkirk JB, Zide SL, Hendee RW, Bowes WA, Hecht F, O'Keeffe D, Henry GP, Shikes RH. A surgical approach to the treatment of fetal hydrocephalus. 1982. PMID: 7070456


  332. Clewell WH, Johnson ML, Meier PR, Newkirk JB, Hendee RW, Bowes WA, Zide SL, Hecht F, Henry G, O'Keeffe D. Placement of ventriculo-amniotic shunt for hydrocephalus in a fetus. 1981. PMID: 7278901


  333. Hecht F, Kaiser-McCaw B, Sandberg AA. Chromosome translocations in cancer. 1981. PMID: 7231485


  334. Hecht F, Kaiser-McCaw B. Position effect in 8;14 translocation in Burkitt's lymphoma. 1981. PMID: 7442741


  335. Hecht F. Prenatal diagnosis: a broader perspective. 1980. PMID: 6445428


  336. Hecht F. The decline of NIH's peer-review system? 1979. PMID: 492248


  337. Meyers DA, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Palmer CG, Rivas ML, Wang L. Linkage group I: multipoint mapping. 1975. PMID: 812567


  338. Meyers DA, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Palmer GC, Rivas ML, Wang L. Linkage group I: multipoint mapping. 1975. PMID: 1192823


  339. Rivas ML, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Meyers DA, Palmer CG, Wang L. Linkage relationships of 1qh to Amy, Fy, PGM1, and Rh. 1975. PMID: 812569


  340. Rivas ML, Conneally PM, Hecht F, Lovrien EW, Magenis E, Merritt AD, Meyers DA, Palmer CG, Wang L. Linkage relationships of 1qh to Amy, Fy, PGM1, and Rh. 1975. PMID: 1192828