David Sears, MD

Associate Professor

David Sears is an Associate Professor of Medicine and a specialist in infectious diseases. He provides HIV primary care in UCSF’s 360: Positive Care Center and attends on the infectious diseases inpatient consult service at UCSF Health and the internal medicine wards at Zuckerberg San Francisco General Hospital. As a clinician educator, David has a particular passion for capacity building to strengthen the HIV primary care workforce locally and abroad. He is the Site Director of the HIV Continuity Clinic for the Infectious Diseases Fellowship at UCSF Health where he leads the 360 Clinic’s educational programs. He also serves as the Senior Medical Education Lead for the Strengthening Interprofessional Education to Improve HIV Care Across Africa (STRIPE) program, where he works with interprofessional teams from health professions schools across sub-Saharan Africa to implement and evaluate HIV training programs that have reached over 20,000 learners.

David is a member of the Academy of Medical Educators (AME) and a prior recipient of the Excellence in Teaching Award from the AME and the Vince Pons Award in Clinical Teaching from the Division of Infectious Diseases. He serves as the Director of the Department of Medicine Medical Student Electives and the Director of the Infectious Diseases elective for medical students at UCSF Health. He was previously the Associate Program Director for the Infectious Diseases Fellowship at Harbor UCLA Medical Center.

Outside of medical education, David’s work focuses on improving the health of people who live and work in prisons and jails through improved health care delivery, reforming conditions of confinement, and advocating for an end to mass incarceration policies. He is the Director of Healthcare Quality for Amend at UCSF where he studies healthcare oversight and quality evaluation in carceral settings with an aim to inform policy and effect meaningful change. Previously, he co-directed a cross-university research collaboration (CalPROTECT) examining how California prisons could better respond to the threat of COVID-19 and he has evaluated the California Department of Corrections and Rehabilitation (CDCR) patient safety and quality assessment programs. He has provided expert testimony to the California State Senate Committee on Public Safety, consulted on draft legislation for the U.S. Senate, prepared independent reports for California’s Federal Receiver for Inmate Services, and presented on carceral health to the National Governor’s Association.

David completed medical school at the Warren Alpert Medical School at Brown University, internal medicine residency at New York Presbyterian Hospital – Columbia, and infectious diseases fellowship at UCSF.
Education
2018 - Diversity, Equity, and Inclusion Champion Training, University of California
Fellowship, 2013 - Infectious Diseases, University of California San Francisco
Residency, 2010 - Internal Medicine, New York Presbyterian Hospital - Columbia
M.D., 2007 - , Alpert Medical School at Brown University
Honors and Awards
  • Vince G. Pons Award in Clinical Teaching, UCSF Infectious Diseases Fellowship, 2022
  • Excellence in Teaching Award, UCSF Haile T. Debas Academy of Medical Educators, 2019
Websites
Publications
  1. Sophia T Tan, Isabel Rodríguez-Barraquer, Ada T Kwan, Seth Blumberg, Justine Hutchinson, David Leidner, Joseph A Lewnard, David Sears, Nathan C Lo. P-2342. Dynamics of indirect protection against SARS-CoV-2 infection through vaccine- and infection-acquired immunity. 2025. PMID:


  2. Tan ST, Rodríguez-Barraquer I, Kwan AT, Blumberg S, Park HJ, Hutchinson J, Leidner D, Lewnard JA, Sears D, Lo NC. Strength and durability of indirect protection against SARS-CoV-2 infection through vaccine and infection-acquired immunity. 2025. PMID: 39881133


  3. Khanyola J, Reid M, Dadasovich R, Derbew M, Couper I, Dassah ET, Forster M, Gachuno O, Haruzivishe C, Kazembe A, Martin S, Moltwantwa M, Motlhatlhedi K, Mteta KA, Nadesan-Reddy N, Suleman F, Ngoma C, Odaibo GN, Mubuuke R, von Zinkernagel D, Kiguli-Malwadde E, Sears D. Improving interprofessional collaboration: building confidence using a novel HIV curriculum for healthcare workers across sub-Saharan africa. 2024. PMID: 39092781


  4. Haber LA, Sears D, Williams BA. Medicaid for Medical-Correctional Care: Time to Manage What is Reimbursed. 2024. PMID: 38831244


  5. Fung M, La Hoz RM, Durand CM, Lee DH, Sears D, Hohe C, Chin-Hong P, Roberts JP. Successful Living Donor Liver Transplant from Donor with False-Positive HIV Test in Recipient without HIV. 2024. PMID: 38705516


  6. Archer H, McCoy SI, Sears D, Kwan A, Kuersten M, Lewnard JA, Bertozzi SM. Indirect vaccine effectiveness in an outbreak of Alpha B.1.1.7 variant in a California state Prison, May 2021. 2024. PMID: 38584059


  7. Sklar R, Noth E, Kwan A, Sear D, Bertozzi S. Ventilation conditions during COVID-19 outbreaks in six California state carceral institutions. 2023. PMID: 37934737


  8. Kiguli-Malwadde E, Forster M, Eliaz A, Celentano J, Chilembe E, Couper ID, Dassah ET, De Villiers MR, Gachuno O, Haruzivishe C, Khanyola J, Martin S, Motlhatlhedi K, Mubuuke R, Mteta KA, Moabi P, Rodrigues A, Sears D, Semitala F, von Zinkernagel D, Reid MJA, Suleman F. Comparing in-person, blended and virtual training interventions; a real-world evaluation of HIV capacity building programs in 16 countries in sub-Saharan Africa. 2023. PMID: 37486898


  9. Tan ST, Kwan AT, Rodríguez-Barraquer I, Singer BJ, Park HJ, Lewnard JA, Sears D, Lo NC. Infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave. 2023. PMID: 36593393


  10. Kwan A, Garcia-Grossman I, Sears D, Bertozzi SM, Williams BA. The Impact Of COVID-19 On The Health Of Incarcerated Older Adults In California State Prisons. 2022. PMID: 35914202


  11. Kiguli-Malwadde E, Forster M, Martin S, Chilemba E, Couper I, Motlhatlhedi K, Celentano J, Haruzivishe C, Sears D, Budak JZ, Khanyola JN, Von Zinkernagel D, Molwantwa M, Semitala F, de Villiers M, Reid M, Kazembe A. Evaluating the impact of a multicountry interprofessional training programme to improve HIV knowledge and clinical confidence among healthcare workers in sub-Saharan Africa: a cohort study. 2022. PMID: 35858724


  12. Blumberg S, Lu P, Kwan AT, Hoover CM, Lloyd-Smith JO, Sears D, Bertozzi SM, Worden L. Modeling scenarios for mitigating outbreaks in congregate settings. 2022. PMID: 35857774


  13. Kwan A, Sklar R, Cameron DB, Schell RC, Bertozzi SM, McCoy SI, Williams B, Sears DA. Respiratory pandemic preparedness learnings from the June 2020 COVID-19 outbreak at San Quentin California State Prison. 2022. PMID: 35678718


  14. Budak JZ, Sears DA, Wood BR, Spach DH, Armstrong WS, Dhanireddy S, Teherani A, Schwartz BS. HIV Training Pathways in Residency: A National Survey of Curricula and Outcomes. 2020. PMID: 32211781


  15. Schnittman SR, Zepf R, Cocohoba J, Sears D. Heplisav-B Seroprotection in People with HIV: A Single-Center Experience. 2020. PMID: 33196553


  16. Sears D, Ahalt C, Augustine D, Williams B. Occupational Health: A Key to the Control of COVID-19 in Correctional Facilities. 2020. PMID: 32716628


  17. Cloud DH, Ahalt C, Augustine D, Sears D, Williams B. Medical Isolation and Solitary Confinement: Balancing Health and Humanity in US Jails and Prisons During COVID-19. 2020. PMID: 32632787


  18. Williams B, Ahalt C, Cloud D, Augustine D, Rorvig L, Sears D.. Health Affairs Blog 2020. PMID:


  19. Sears D, Schwartz BS. Candida auris: An emerging multidrug-resistant pathogen. 2017. PMID: 28888662


  20. Spier AB, Kurtz J, Sears D. A novel case of lymphangiomatosis in HIV. 2017. PMID: 28189546


  21. Sserwanga A, Sears D, Kapella BK, Kigozi R, Rubahika D, Staedke SG, Kamya M, Yoon SS, Chang MA, Dorsey G, Mpimbaza A. Anti-malarial prescription practices among children admitted to six public hospitals in Uganda from 2011 to 2013. 2015. PMID: 26306395


  22. Mpimbaza A, Sears D, Sserwanga A, Kigozi R, Rubahika D, Nadler A, Yeka A, Dorsey G. Admission Risk Score to Predict Inpatient Pediatric Mortality at Four Public Hospitals in Uganda. 2015. PMID: 26218274


  23. Sears D, Mpimbaza A, Kigozi R, Sserwanga A, Chang MA, Kapella BK, Yoon S, Kamya MR, Dorsey G, Ruel T. Quality of inpatient pediatric case management for four leading causes of child mortality at six government-run Ugandan hospitals. Volume 10 of Issue 5. 2015. PMID: 25992620


  24. Sears D, Kigozi R, Mpimbaza A, Kakeeto S, Sserwanga A, Staedke SG, Chang M, Kapella BK, Rubahika D, Kamya MR, Dorsey G. Anti-malarial prescription practices among outpatients with laboratory-confirmed malaria in the setting of a health facility-based sentinel site surveillance system in Uganda. Volume 12. 2013. PMID: 23870515


  25. Neuberg GW, Stephenson KE, Sears DA, McConnell RJ. Internet-enabled thyroid hormone abuse. 2009. PMID: 19124828


  26. Sears D, Cabrera-Rodriguez C, Ortiz-Mejia F, Anderson B, Stein M. Sexual risk behaviour among HIV-positive patients at an urban clinic in Santiago, Dominican Republic. 2008. PMID: 18293128