Science translational medicine
Autologous neutralizing antibodies increase with early antiretroviral therapy and shape HIV rebound after treatment interruption.
Malaria-driven expansion of adaptive-like functional CD56-negative NK cells correlates with clinical immunity to malaria.
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies.
Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19.
The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance.
New blood: Creative funding of disease-specific research.
In utero priming of highly functional effector T cell responses to human malaria.
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.
Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism.
Semen enhances HIV infectivity and impairs the antiviral efficacy of microbicides.